目的 了解消化性溃疡发病特点,分析溃疡在秋冬和冬春之交发病情况的差异。方法 对我院10年胃镜检查结果进行统计分析。结果 共检出消化性溃疡8592例,其中十二指肠溃疡6875例,胃溃疡1121例,复合性溃疡596例,三者的检出率分别为12.72%、2.07%和1.10%,十二指肠溃疡明显多于胃溃疡,两者之比为6.13∶1。季节上,十二指肠溃疡与胃溃疡的检出率在秋冬之交高于春冬之交,十二指肠溃疡的检出率在春冬季高于夏秋季,复合性溃疡在冬季高发,秋季最低。胃溃疡好发于胃窦,其次是胃角;十二指肠球部溃疡的好发部位依次为前壁、大弯、小弯、后壁。十二指肠溃疡、胃溃疡和复合性溃疡的高发年龄段为30~39岁、40~49岁和 40~59岁。结论 十二指肠溃疡明显多于胃溃疡,十二指肠溃疡与胃溃疡的检出率在秋冬之交高于春冬之交。消化性溃疡的发病在性别、年龄、季节等方面上具有明显差异。

Objective To explore the features of peptic ulcer disease, and analyze difference of incidence in difference months. Methods Gastroscopy results were collected and analyzed in our hospital. Results A total of 8592 cases of peptic ulcer were collected, including 6875 cases of duodenal ulcer, 1121 cases of gastric ulcer and 596 cases of compound ulcer, the detection rate were 12.72%, 2.07% and 1.10% respectively. Duodenal ulcer presented significantly more than gastric ulcer, the ratio was 6.13∶1. As to season changed, the detection rate of duodenal ulcer and gastric ulcer in the months when autumn turns winter were higher than in the months when winter turns spring. The detection rate of duodenal ulcers in winter and spring were higher than summer and autumn. Compound ulcer had highest incidence in winter and lowest in autumn. As to predilection site, gastric ulcer was mainly in gastric antrum, followed by gastric angle, duodenal ulcer was mainly in anterior wall. The peak age of duodenal ulcer, gastric ulcer and compound ulcer were 30~39, 40~49, and 40~59 years old. Conclusion Duodenal ulcer was remarked more than gastric ulcer. The detection rate of duodenal ulcer and gastric ulcer in the months when autumn turns winter was high than in the months when winter turns spring. The incidence of peptic ulcer has obvious differences in gender, age, season, etc.

目的 观察多西环素联合阿莫西林、泮托拉唑、枸橼酸铋钾治疗幽门螺杆菌(Hp)感染消化性溃疡的临床疗效和不良反应。方法 选取于2013年7月—2015年7月收治的98例Hp感染消化性溃疡患者,根据不同的治疗方式,随机将其分为治疗组和对照组,每组各49例,治疗组患者给予多西环素联合阿莫西林、泮托拉唑、枸橼酸铋钾治疗;对照组给予克拉霉素联合阿莫西林、泮托拉唑、枸橼酸铋钾治疗, 两组患者连续服用10天后,均口服泮托拉唑40 mg,每天1次,总疗程为4周。疗程结束4周后,予胃镜复查和Hp检查,观察两组患者的临床疗效、溃疡愈合率、Hp根除率及不良反应。结果 治疗组与对照组患者的临床效果总有效率分别是95.91％、81.63％;治疗组与对照组患者的溃疡愈合率分别是83.67％、61.22％ ;治疗组与对照组患者的Hp根除率分别是89.79％、65.30％;治疗组患者的临床疗效总有效率、溃疡愈合率和Hp根除率均明显优于对照组,差异均有统计学意义(P<0.05),两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论 多西环素联合阿莫西林、泮托拉唑、枸橼酸铋钾治疗Hp感染消化性溃疡疗效显著、溃疡愈合率高、Hp根除率高、且安全无明显不良反应,值得临床广泛推广使用。

目的 研究并分析优质护理对消化性溃疡患者的临床疗效以及护理满意度的影响。方法 入选2014年8月—2015年10月收治的184例消化性溃疡患者作为研究对象, 根据电脑随机数字将患者随机分为研究组和对照组,各92例。对照组男50例,女42例,年龄18～60 a,平均年龄(43.7±2.1)a,病程2～10 a,平均(5.2±0.4)a,研究组男48例,女44例,年龄20～59 a,平均(42.3±3.6)a,病程2～10 a,平均(5.2±0.4)a。患者入院后均给予消化性溃疡常规基础治疗(四联疗法),在此基础上给予对照组患者常规护理,研究组患者优质护理,对比两组患者的临床疗效和护理满意度。结果 经研究观察对比,研究组消化性溃疡患者的临床疗效明显优于对照组,研究组消化性溃疡患者的总有效率为95.65%,对照组为79.35%,两组数据对比差异有统计学意义(P＜0.05)。研究组患者治疗后烧心、上腹痛、嗳气等症状减轻明显较对照组显著,所需时间更短,胃镜检查显示研究组患者经优质护理处理后溃疡愈合时间明显缩短,愈合明显优于对照组,上述对比差异有统计学意义(P＜0.05)。研究组护理满意度为96.74%,对照组护理满意度仅83.69%,研究组高于对照组,差异有统计学意义(P＜0.05)。结论 优质护理能够明显缩短溃疡愈合时间,促进患者痊愈,提高消化性溃疡患者的疗效和护理满意度,值得临床推广和应用。

Objective To study and analyze the effect of high quality nursing on curative effect of patients with peptic ulcer and nursing satisfaction. Methods 98 cases of peptic ulcer patients income for treatment from August 2014 to October 2015 were selected as study subjects. The patients were randomly divided into study group and control group, 49 cases in each group. The control group included male 28 case,female 21 case,aged 18～60 years old, average age (43.7±2.1) years, disease duration of(2～10)years, average(5.2±0.4) years.Study group included male 24 cases, female 25 cases, aged 20～59 years old, average age (42.3±3.6) years, disease duration of (2～10) years, average (5.2±0.4) years. After the patient was admitted to hospital, they were treated with digestive ulcer routine treatment (quadruple therapy). On this basis,patients in the control group were given routine nursing care, the study group patients with high quality nursing, compared with the two groups of patients with clinical efficacy and nursing satisfaction. Results Study group patients with peptic ulcer clinical, curative effect was obviously superior to the control group. The study group patients with peptic ulcer, total efficiency was 95.91%, It was 79.59% in the control group, the difference between the data of two groupshad statistical significance (P<0.05). Study group nursing satisfaction was 97.96%, the control group was only81.63%. The study group was significantly higher than the control group, the difference was statistically significant (P<0.05). Quality care may significantly shorten the average length of stay in patients, the difference was statistically significant (P<0.05). Conclusion High quality nursing may significantly shorten the average length of stay in patients with peptic ulcer, improve the curative effect of peptic ulcer patients and nursing satisfaction. It is worthy of clinical popularization and application.