For students who majored in clinical medicine,biochemistry is a crucial foundation course,and the teaching quality of which directly influence the educational objectives of clinical medicine students.In this study,we explored the teaching reformation methods of biochemistry course under the background of New Medicine.We integrated ideological elements into classroom teaching,and used various teaching methods in the classroom,built an open experiment platform and innovated course assessment mode,for trying to improve the students’ ability of self-study,clinical problems resolving and scientific literacy.