目的 探讨在小剂量催产素基础上分别联合普贝生和COOK宫颈扩张球囊对足月妊娠引产的临床效果。方法 抽取110例足月妊娠孕妇住院资料,根据引产方式不同分为两组,各55例。A组采用小剂量催产素引产,B组在A组基础上加用COOK球囊引产,比较两组促宫颈成熟效果、母婴结局以及不良并发症情况。结果 两组孕妇引产前后Bishop 评分相比,差异显著（P<0.01）,此外,与A组相比,B组引产后Bishop 评分升高（P<0.01）。A组促宫颈成熟效果有效人数为48例,新生儿Apgar 评分为9.12±2.11,产后出血量（210.7±55.44）mL,阴道分娩人数为40例,而B组引产过程中各指标均显著改善。此外,B组未出现宫内感染和胎盘早剥,而胎儿窘迫和其他并发症降低（P<0.01）。结论 催产素联合COOK球囊对足月妊娠孕妇促宫颈成熟效果显著,降低剖腹产,母婴状态良好,减少不良并发症发生。

目的 探讨COOK双球囊导管和欣普贝生引产的优劣性。方法 选择住院分娩的孕妇388例,根据引产方式分为两组,研究组应用COOK双球囊导管,对照组应用欣普贝生。根据宫颈Bishop评分,研究组分为研究组1和研究组2,对照组分为对照组1和对照组2,研究组1和对照组1宫颈Bishop评分小于或等于3分,研究组2和对照组2宫颈Bishop评分大于3分而小于或等于6分。分别对各组促宫颈成熟及引产情况、妊娠结局进行比较。结果 各组放置COOK宫颈双球囊或欣普贝生前后,宫颈Bishop评分有差异,低宫颈Bishop评分组欣普贝生效果更好。研究组与对照组比较,阴道分娩和剖宫产病例差异无统计学意义;急产、产后出血、羊水污染病例差异有统计学意义。研究组新生儿窒息率低于对照组,体温>37.5℃发生率高于对照组,差异无统计学意义。结论 对宫颈条件较差者,建议选用欣普贝生诱导宫颈成熟;COOK双球囊导管引产,作用温和,安全性好,成功率高。

Objective To evaluate the advantage of the COOK double balloon catheter and Propess induced labor. Methods We collected 388 cases with pregnant women. The patients were divided into the research and control groups. The research group applied COOK double balloon catheter while the control group applies Propess. According to cervical Bishop rating, the research team was divided into research group 1 and research group 2. The control group was divided into control group 1 and the control group 2. The cervical Bishop score of the research group 1 and control group 1 was less than or equals 3 points. The cervical Bishop score of the research group 2 and the control group 2 was greater than 3 and less than or equal 6 points. We separately compared the pregnancy outcome for each group to promote cervical mature and induced labor situation. Results The cervical Bishop scores have significant difference before and after COOK cervical double balloon and Propess are positioned between two groups.The effect of low cervical Bishop scores group is better than the high cervical Bishop by propess. The rates of urgent production, postpartum hemorrhage and amniotic fluid pollution reduce significant in the research group. The neonatal asphyxia rate, incidence of temperature > 37.5, vaginal delivery cases and cesarean section cases have not significant differences between the research group and the control group. Conclusion We suggest that patients whose cervical condition is poor should choose Propess induced cervical mature; The COOK double balloon catheter induced labor is safe and has a high success rate.