论著
目的 研究基于儿童早期预警评分(PEWS)的分级干预模式促进重症肺炎患儿康复进程及对呼吸功能的影响。方法 回顾性分析2021年4月—2023年4月我院收治的100例重症肺炎患儿临床资料。将其按照干预方式的差异分为研究组(n=50)及对照组(n=50)。对照组选用常规干预,研究组则于对照组基础上增加基于PEWS的分级干预。对比两组康复进程(相关指标涵盖症状持续时长及住院天数)、呼吸功能(涵盖通气流速、每分钟最大通气量、肺活量、用力肺活量及深吸气量)、并发症发生情况(涵盖呼吸机相关性肺炎、肺大疱及胸膜炎)、患儿家属满意度。结果 研究组各项症状持续时长及住院天数均短于对照组(均P<0.05)。研究组各项呼吸功能指标水平均高于对照组(均P<0.05)。两组各项并发症发生率对比差异无统计学意义(P>0.05)。研究组患儿家属满意度高于对照组(96.00% vs 82.00%,P<0.05)。结论 基于PEWS的分级干预模式促进重症肺炎患儿康复进程的效果较佳,且能改善呼吸功能,提高患儿家属满意度。
Objective To study the effect of graded intervention mode based on Pediatric Early Warning Score(PEWS)on the recovery process and respiratory function of children with severe pneumonia.Methods The clinical data of 100 children with severe pneumonia treated in our hospital from April 2021 to April 2023 were retrospectively analyzed.Those children were divided into study group(n=50)and control group(n=50)according to the difference of intervention methods.Conventional intervention was used in the two groups,and PEWS-based graded intervention was added to the study group.The two groups were compared with each other in terms of recovery process(including duration of symptoms and length of stay),respiratory function(including ventilation velocity,maximum volume per minute,vital capacity,forced vital capacity and deep inspiratory capacity),complications(including ventilators associated pneumonia,bullosa and pleurisy),and family member satisfaction.Results The duration of symptoms and hospitalization days in the study group were shorter than those in the control group(all P<0.05).The levels of respiratory function indexes in study group were higher than those in control group(all P<0.05).There was no significant difference in the incidence of complications between the two groups(P>0.05).The satisfaction of family member in the study group was higher than that in the control group(96.00% vs 82.00%)(P<0.05).Conclusions The PEWS based graded intervention model has a good effect on promoting the rehabilitation process of children with severe pneumonia,and can improve respiratory function,and increase the satisfaction of family member of children with severe pneumonia.
论著
目的 探讨苏黄止咳胶囊联合多索茶碱对慢性持续期支气管哮喘的疗效及对肺功能、呼出气一氧化氮(FeNO)的影响。方法 选择2020年3月—2022年3月70例慢性持续期支气管哮喘患者,随机分为2组各35例,对照组仅予以多索茶碱治疗,研究组在对照组基础上加服苏黄止咳胶囊治疗。治疗3个月,采用哮喘控制测试(ACT)对患者进行评估,记录哮喘急性加重、急救药物使用情况及急诊入院情况,测定肺功能和呼出FeNO。结果 2组治疗1月的ACT评分比较无统计学意义(P>0.05),治疗2、3个月时研究组的ACT评分高于对照组(P<0.05)。研究组哮喘急性加重次数、急救药物使用次数均少于对照组(P<0.05),而2组急诊入院次数比较差异无统计学意义(P>0.05)。与基线值相比,2组治疗3个月时的肺功能指标无改变(P>0.05)且组间比较差异亦无统计学意义(P>0.05);2组治疗3个月时的FeNO无改变(P>0.05),而研究组的FeNO低于对照组(P<0.05)。结论 苏黄止咳胶囊联合多索茶碱治疗慢性持续期支气管哮喘可降低FeNO,提高哮喘控制水平。
Objective To investigate the effect of Suhuang Zhike capsule combined with doxofylline on chronic persistent bronchial asthma, pulmonary function and exhaled nitric oxide(FeNO).Methods Seventy patients with chronic persistent bronchial asthma from March 2020 to March 2022 were randomly divided into two groups, 35 cases in each group.The control group was only treated with doxofylline, and the study group was treated with Suhuang Zhike capsule additionally.After 3 months of treatment, the patients were evaluated by asthma control test(ACT), the acute exacerbation of asthma was recorded, and the pulmonary function and exhaled FeNO were measured.Results There was no statistical significance in the ACT score of the two groups after one month of treatment(P>0.05).The ACT scores of the study group after two months and three months of treatment were significantly higher than those of the control group(P<0.05).The times of acute exacerbation of asthma and the use of emergency drugs in the study group were less than those in the control group(P<0.05), but there was no significant difference in the number of emergency hospitalizations between the two groups(P>0.05).Compared with the baseline value, there was no significant change in lung function indexes in the two groups after 3 months of treatment(P>0.05).Compared with the baseline value, there was no significant change in FeNO in the two groups after 3 months of treatment(P<0.05), while FeNO in the study group was lower than that in the control group(P<0.05).Conclusions Suhuang Zhike capsule combined with doxofylline in the treatment of chronic persistent bronchial asthma can reduce FeNO and improve the level of asthma control.