目的 探讨扩张型心肌病采用诺欣妥治疗的效果及对其心功能的影响。方法 本文将2020年2月—2020年10月收治的扩张型心肌病患者50例作为研究对象,对所有患者按照随机方式进行分组,对照组25例患者以常规抗心衰治疗与依那普利治疗,观察组25例患者在常规抗心衰治疗的基础上给予诺欣妥治疗,统计分析用药后有效率、治疗前后心功能指标、6 min步行距离及炎症因子水平。结果 两组之间炎症因子水平相比,观察组较对照组低;6 min步行距离、用药后有效率相比,观察组较对照组高;心功能指标相比,观察组SV、LVEF较对照组高,LVESD、LVEDD较对照组低,P＜0.05。结论 采用诺欣妥治疗扩张型心肌病效果显著,总有效率较好,可有效改善患者心功能指标,增加6 min步行距离,减轻炎症因子水平,改善患者预后。

目的 分析影响接受夫精宫腔内人工授精(IUI)助孕患者临床妊娠率的有关因素。方法 选择225例接受IUI助孕共400周期的不孕症患者,回顾分析女方年龄、治疗方案、hCG日子宫内膜厚度、IUI周期数与临床妊娠率的关系。结果 女方年龄>38岁的临床妊娠率(8.22%)低于年龄<30岁(21.74%)和30~38岁(17.48%),P<0.05;促排卵方案(CC、HMG、CC+HMG)临床妊娠率分别为19.05%、19.66%和14.71%,高于自然周期的临床妊娠率7.14%,P<0.05;hCG日子宫内膜厚度≥8 mm组的临床妊娠率(23.56%)高于内膜<8 mm组的临床妊娠率(13.27%),P<0.05;第1至第5周期的IUI临床妊娠率分别为21.30%、15.60%、9.38%、0%和0%,多次重复IUI周期数差异有统计学意义(P<0.05)。结论 女方年龄、hCG日子宫内膜厚度、治疗方案均会影响IUI的临床妊娠率,但增加IUI的治疗周期数并不能提高临床妊娠率,应综合各种因素再次评估患者的妊娠率,必要时进一步查找多次助孕失败的原因或改行IVF-ET助孕治疗。

Objective To analyze the relative factors which influence the clinical pregnancy rates of patients accepted intrauterine insemination with husband's sperm. Methods 225 cases of infertile patients accepted IUI treatment were selected, 400 cycles were included and the clinical data were analyzed retrospectively. Observing the relationship between the age of women, treatment options, endometrial thickness on hCG injection day, cycles of IUI and pregnancy rates. Results The clinical pregnancy rates of women less than 30 years old(21.74%) were higher than aged between 30 to 38 years old(17.48%) and more than aged 38 years old(8.22%), P<0.05.The clinical pregnancy rates of ovulation induction options(CC、HMG、CC+HMG) were 19.05%, 19.66% and 14.71%, higher than the pregnancy rates of natural cycle 7.14% significantly, P<0.05. The pregnancy rates of the group of endometrial thickness ≥8mm on hCG injection day were 23.56%, higher than the group of endometrial thickness <8 mm 13.27%, P<0.05. The clinical pregnancy rates of 1 to 5 cycles IUI were 21.30%, 15.60%, 9.38%, 0% and 0% respectively, the difference of repeating the IUI cycles’ number was statistical significance (P<0.05). Conclusion The ages of women, endometrial thickness on hCG injection days and treatment options can affect the clinical pregnancy rates. Extending the number of IUI treatment cycles can not increase the pregnancy rates of IUI. All the factors should be comprehensive to assess the patient's pregnancy rates again, to find more reasons further for the failure of assisted reproduction or turn to IVF-ET assisted reproduction treatment when it is necessary.

目的 探讨盆底肌康复仪配合中药补中益气汤对盆底功能障碍性疾病的治疗疗效。方法 对300例女性盆底功能障碍性疾病(FPFD)的患者采用盆底肌康复仪同时配合中药补中益气汤协同治疗从而弥补单纯盆底康复治疗不足。结果 产后一年内的早期盆底肌力松弛治愈率达83.82%; SUI组治疗后的临床症状控制效果及盆底肌力、持续时间优于POP组,P＜0.01。结论 产后及时、早期干预盆底肌功能可有效防止盆底功能障碍性疾病的不良发展,同时配合经典方补中益气汤可益气、升阳举陷调理脏腑机能产生协同作用。