论著

产后出血预测评分与凝血指标的关联及对阴道分娩产后出血的预测效能分析

Correlation between postpartum bleeding prediction score and coagulation index and analysis of their prediction efficiency of postpartum bleeding in vaginal delivery

:59-63
 
目的 分析产后出血预测评分与产妇凝血指标的相关性,以及出血预测评分对阴道分娩产后出血的预测效能。方法 采用回顾性研究,纳入2021年1月—2022年12月河南科技大学第二附属医院收治的136例阴道分娩产妇,根据产后出血情况,将合并产后出血的36例患者列为病例组,其余100例列为对照组,比较两组患者的产后出血预测评分及凝血指标,经Spearman相关性系数验证产后出血预测评分结果与凝血指标的相关性,依据实际出血情况,验证产后出血预测评分、各凝血指标对产后出血的预测效能。结果 病例组患者的产后出血预测评分为(7.33±2.46)分,D-二聚体(D-D)为(2.62±0.41)mg/L,均高于对照组[(6.14±2.06)分、(2.17±0.45)mg/L],纤维蛋白原(FIB)为(4.42±1.25)g/L,低于对照组(5.23±1.16)g/L;活化部分凝血活酶时间(APTT)为(37.44±10.25)s,凝血酶原时间(PT)为(15.45±4.12)s,凝血酶时间(TT)为(16.77±4.25)s,均高于对照组[(30.11±10.12)s、(12.49±4.11)s、(13.34±4.18)s],差异具有统计学意义(P<0.05)。经Spearman相关性系数分析,产后出血预测评分与经阴道分娩产妇的D-D、APTT、PT、TT呈正相关,与FIB呈负相关。通过绘制受试者工作特征曲线(ROC)后得知,产后出血预测评分及凝血指标对产后出血均有一定预测价值,但产后出血预测评分的AUC值大于各凝血指标。结论 产后出血预测评分与产妇凝血功能指标呈正相关,将产后出血预测评分与凝血指标检测相结合能实现对产后出血的早期识别及诊断。
Objective To analyze the correlation between postpartum bleeding prediction score and maternal blood coagulation index and the prediction efficiency of postpartum bleeding in vaginal delivery.Methods This is a retrospective study.The cases were included from January 2021 to December 2022.The subjects of the study were 136 vaginal delivery mothers. According to the delivery situation,36 patients with postpartum bleeding were included in the case group,and the rest 100 patients were included in the control group.The postpartum bleeding prediction score and coagulation indicators of the two groups were compared.The correlation between postpartum bleeding prediction score and coagulation indicators was verified by Spearman correlation coefficient.According to the actual bleeding situation,verify the predictive score for postpartum bleeding and the diagnostic efficacy of various coagulation indicators on postpartum bleeding.Results According to the test,the predictive score for postpartum bleeding in the case group was(7.33±2.46),D-dimer(D-D)was(2.62±0.41)mg/L,which were higher than those in the control group [(6.14±2.06),(2.17±0.45)mg/L].Fibrinogen(FIB)was(4.42±1.25)g/L,lower than the control group(5.23±1.16)g/L,activated partial thromboplastin time(APTT)was(37.44±10.25)s,prothrombin time(PT)was(15.45±4.12)s,and thrombin time(TT)was(16.77±4.25)s.Compared with the control group [(30.11±10.12)s,(12.49±4.11)s,and(13.34±4.18)s)],the above indicators were all higher(P<0.05).Through Spearman correlation coefficient analysis,the predictive score of postpartum bleeding was positively correlated with the D-D,APTT,PT,TT,negatively correlated with the FIB of the parturient who delivered through vagina.After drawing the ROC curve,it was found that both the postpartum hemorrhage prediction score and coagulation indicators had certain predictive value for postpartum hemorrhage,but the AUC value of the postpartum hemorrhage prediction score was greater than each coagulation indicator.Conclusions The prediction score of postpartum bleeding is positively correlated with the coagulation function indicators of the parturient,combining the score and indicators can achieve early identification and diagnosis of postpartum bleeding.
临床诊疗

一次性囊式宫颈扩张器用于治疗产后出血的临床研究

Clinical study of disposable type cervical dilator in the treatment of postpartum hemorrhage

:102-104
 
目的 探讨产后出血(PPH)应用一次性囊式宫颈扩张器治疗的临床效果。方法 选取我院2001年1月—2016年12月收治的50例PPH产妇,按就诊先后顺序进行分组,2001年1月—2015年12月就诊的25例为对照组(予以宫腔填塞纱布治疗);2016年1月—2016年12月就诊的25例为观察组(给予一次性囊式宫颈扩张器治疗),并按照分娩方式不同分为阴道分娩组(15例),剖宫产组(10例)。记录比较观察组和对照组的治疗与预后情况;阴道分娩组与剖宫产组的治疗情况。结果 与对照组比较,观察组在操作时间、填塞物留置时间及起效时间方面,均显著更优(P<0.01);两组放置后12 h出血量、显效率相比,差异无统计学意义(P>0.05);观察组子宫切除、子宫动脉结扎及产褥感染等发生率均低于对照组,但差异均无统计学意义(P>0.05);阴道分娩组的起效时间、留置时间、T2时间段阴道总流血量、显效率及产褥感染率,较剖宫产组比较,差异均无统计学意义(P>0.05),阴道分娩组T1时间段阴道总流血量显著低于剖宫产组(P<0.01)。结论 PPH产妇应用一次性囊式宫颈扩张器治疗操作简便,更有利于缩短操作时间,改善预后,效果切实,且对于阴道分娩与剖宫产产妇的疗效相当,适用于基层医院,具有较高临床推广价值。
临床诊疗

限制会阴切开及会阴不同切口对产妇产后出血、疼痛及性功能的影响

Effect of Episiotomy Limit and Different Perineum Incision to Postpartum Hemorrhage, Pain and Sexual Function

:73-74
 
目的 研究限制会阴切开及会阴不同切口对产妇产后出血、疼痛及性功能的影响。方法 选取我院2012年4月—2013年4月头位自然分娩产妇480例,抽签随机分为三组,每组160例,实施限制会阴切开的为限制组,实施会阴侧切的为侧切组,实施会阴正中切开的为正切组,比较三组产妇产后2 h出血量、产后住院时间、产妇会阴阴道裂伤率、产后疼痛程度和性功能满意程度。结果 产后2 h产妇出血量限制组(203.65±76.68)mL较侧切组(241.41±80.63)mL和正切组(239.15±85.19)mL少(P<0.05);侧切组(1.64±0.87)d产后住院时间较限制组(1.37±0.64)d较长(P<0.05);限制组会阴Ⅰ/Ⅱ°裂伤率为86.25%较侧切组1.25%和正切组6.88%较高(P<0.05);侧切组2.50%和正切组3.13%会阴Ⅲ/Ⅳ°裂伤较限制组0%较高(P<0.05);女性性功能指数限制组(22.69±2.65)分较侧切组(19.12±2.05)分与正切组(18.96±2.16)分较高(P<0.05)。结论 实施限制会阴切开的产妇术后出血量少,会阴重度裂伤率低,保证了会阴完整性,产后性功能满意度高,值得临床上应用推广。
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