Objective: To explore the relationship between prenatal psychological resilience support and coping styles of postpartum patients, and to examine the mediating effect of psychological resilience. Methods: Convenience sampling was used to recruit 350 patients at 1-6 months postpartum from March 2025 to March 2026. A retrospective survey was conducted using a general information questionnaire, the Prenatal Psychological Resilience Support Scale, the Connor-Davidson Resilience Scale (CD-RISC), and the Simplified Coping Style Questionnaire (SCSQ). Pearson correlation analysis was performed to examine relationships among variables, hierarchical regression analysis was conducted to test the total effect, and the PROCESS macro Model 4 with bootstrapping was employed to test the mediating effect. Results: Prenatal psychological resilience support was significantly positively correlated with positive coping (r = 0.30, P<0.01) and significantly negatively correlated with negative coping (r=?0.21, P<0.01). Prenatal psychological resilience support significantly and positively predicted positive coping (β = 0.28, P<0.001) and significantly and negatively predicted negative coping (β=?0.19, P<0.001). The indirect effect of psychological resilience between prenatal psychological resilience support and positive coping was 0.12 (95% CI: 0.08-0.17), and the indirect effect between prenatal psychological resilience support and negative coping was ?0.07 (95% CI: ?0.11 to ?0.04); the direct effects were not significant, indicating a full mediating role of psychological resilience. Conclusion: The impact of prenatal psychological resilience support on postpartum coping styles is fully mediated by psychological resilience, suggesting that perinatal mental health care should focus on internalizing external support into maternal psychological resources and enhancing psychological resilience to promote positive postpartum coping.