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艾滋病继发真菌感染患者病情的临床特点与治疗措施分析

Analysis of clinical characteristics and treatments of AIDS secondary fungal infection

来源期刊: 广州医药 | 37-39 发布时间:2021-11-25 收稿时间:2025/11/13 18:11:44 阅读量:9
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关键词:
艾滋病继发真菌感染病情临床特点治疗措施
AIDS secondary fungal infectionClinical characteristics of the diseaseTreatment measures
DOI:
10.3969/j.issn.1000-8535.2021.02.008
收稿时间:
2020-12-07 
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0  
目的 探讨艾滋病继发真菌感染患者病情的临床特点与治疗措施。方法 选取2019年4月—2020年4月我院收治的艾滋病继发真菌感染患者90例,对所有患者的病情特点进行分析,并及时采取有效地治疗措施。分析患者真菌感染部位、病情临床特点、治疗效果。结果 患者真菌感染部位中,排在前三位的为口腔、肺、食道,占比为44.4%(40/90)、30.0%(27/90)、23.3%(21/90);90例患者中,感染真菌排在前三位的为白色念珠菌、马尔尼菲青霉菌、新型隐球菌,占比为36.7%(33/90)、24.4%(22/90)、16.7%(15/90);90例患者中,显效32例(35.5%)、有效46例(51.1%)、无效12例(13.4%),有效率为86.6%(78/90)。结论 艾滋病继发真菌感染患者中,感染的主要部位主要为口腔、肺、食道,其中感染的真菌主要有白色念珠菌、马尔尼菲青霉菌、新型隐球菌。对患者及时进行有效地抗逆转录病毒治疗可以降低患者死亡率,提高治疗效果。
Objective To explore the clinical characteristics and treatments of AIDS secondary fungal infection. Methods A total of 90 patients with secondary fungal infection of AIDS admitted to our hospital from April 2019 to April 2020 were selected, and the characteristics of all patients were analyzed, and effective treatment measures were taken in time. The sites of fungal infection, clinical characteristics and therapeutic effects were analyzed. Results The top three fungal infection sites were oral cavity, lung and esophagus, accounting for 44.4% (40/90), 30.0% (27/90) and 23.3% (21/90). Among the 90 patients, candida albicans, penicillium marneffei and cryptococcusneoforme ranked the top three, accounting for 36.7% (33/90), 24.4% (22/90) and 16.7% (15/90). Of the 90 patients, 32 had obvious effects (35.5%), 46 had effective effects (51.1%) and 12 had no effects (13.4%), and the effective rate was 86.6% (78/90). Conclusion In the patients with secondary fungal infection of AIDS, the main sites of infection were oral cavity, lung and esophagus, in which the main infected fungi were candida albicans, penicillium marneffei and cryptococcus neofordii. Timely and effective antiretroviral therapy can reduce the mortality and improve the treatment effect.
1、 SHARMAA P, MCCARTYA T R, LANGEA A, et al. Impact of bariatric surgery in patients with HIV infection: A nationwide inpatient sample analysis, 2004-2014[J]. Aids, 2018, 32(14):1959-1965. SHARMAA P, MCCARTYA T R, LANGEA A, et al. Impact of bariatric surgery in patients with HIV infection: A nationwide inpatient sample analysis, 2004-2014[J]. Aids, 2018, 32(14):1959-1965.
2、 何小庆,刘敏,鲁雁秋,等.获得性免疫缺陷综合征合并细菌或真菌性血流感染166例临床分析[J]. 中国感染与化疗杂志,2018,18(6):20-24. 何小庆,刘敏,鲁雁秋,等.获得性免疫缺陷综合征合并细菌或真菌性血流感染166例临床分析[J]. 中国感染与化疗杂志,2018,18(6):20-24.
3、 班杨杰. 艾滋病患者口腔真菌感染的临床特征分析[J]. 临床医药文献电子杂志, 2020, 7(26):16-17. 班杨杰. 艾滋病患者口腔真菌感染的临床特征分析[J]. 临床医药文献电子杂志, 2020, 7(26):16-17.
4、 CORMA-GóMEZ, A, MORANO L, TéLLEZ, F, et al. HIV infection does not increase the risk of liver complications in hepatitis C virus-infected patient with advanced fibrosis, after sustained virological response with direct-acting antivirals[J]. AIDS, 2019, 33(7):1167-1174. CORMA-GóMEZ, A, MORANO L, TéLLEZ, F, et al. HIV infection does not increase the risk of liver complications in hepatitis C virus-infected patient with advanced fibrosis, after sustained virological response with direct-acting antivirals[J]. AIDS, 2019, 33(7):1167-1174.
5、 姜辉,张秋彬,朱华栋,等.非艾滋病耶氏肺孢子菌肺炎患者合并巨细胞病毒血症的危险因素分析[J]. 中华急诊医学杂志,2018,27(9):1004-1009. 姜辉,张秋彬,朱华栋,等.非艾滋病耶氏肺孢子菌肺炎患者合并巨细胞病毒血症的危险因素分析[J]. 中华急诊医学杂志,2018,27(9):1004-1009.
6、 蔡妙甜,范春蕾,李磊,等.艾滋病肝脓肿患者临床特征的对照分析[J]. 中国感染与化疗杂志,2019,19(5):465-472. 蔡妙甜,范春蕾,李磊,等.艾滋病肝脓肿患者临床特征的对照分析[J]. 中国感染与化疗杂志,2019,19(5):465-472.
7、 CAO C W, LI Y. Talaromycosis(penicilliosis) due to talaromyces (penicillium) marneffei: insights into the clinical trends of a major fungal disease 60 years after the discovery of the pathogen.[J]. Mycopathologia, 2019, 184(6):709-720. CAO C W, LI Y. Talaromycosis(penicilliosis) due to talaromyces (penicillium) marneffei: insights into the clinical trends of a major fungal disease 60 years after the discovery of the pathogen.[J]. Mycopathologia, 2019, 184(6):709-720.
8、 石鹏辉,刘书兰,孙文龙,等.艾滋病患者合并真菌感染病原学及危险因素分析[J]. 中华医院感染学杂志,2020,30(9):61-64. 石鹏辉,刘书兰,孙文龙,等.艾滋病患者合并真菌感染病原学及危险因素分析[J]. 中华医院感染学杂志,2020,30(9):61-64.
9、 李丹,龙云铸,周家玉,等.艾滋病合并血流感染的临床特征和病原菌分布[J]. 中国艾滋病性病,2020,26(4):87-89. 李丹,龙云铸,周家玉,等.艾滋病合并血流感染的临床特征和病原菌分布[J]. 中国艾滋病性病,2020,26(4):87-89.
10、 江华. 艾滋病患者继发真菌感染临床分析[J]. 包头医学院学报, 2015, (3):56-57. 江华. 艾滋病患者继发真菌感染临床分析[J]. 包头医学院学报, 2015, (3):56-57.
11、 李旭东. 艾滋病真菌感染临床回顾[C]//中华中医药学会防治艾滋病分会2018年学术年会. 李旭东. 艾滋病真菌感染临床回顾[C]//中华中医药学会防治艾滋病分会2018年学术年会.
12、 杨丹丹,张桂仙,赵自屹,等. 艾滋病合并马尔尼菲篮状菌感染的流行病学及临床特点分析[J]. 中国病原生物学杂志,2020,56(5):497-502. 杨丹丹,张桂仙,赵自屹,等. 艾滋病合并马尔尼菲篮状菌感染的流行病学及临床特点分析[J]. 中国病原生物学杂志,2020,56(5):497-502.
13、 RUDEN M, OLIVARES C, FAKHOURY M Q, et al. Prostate cancer presentation, treatment selection, and outcomes among men with HIV/AIDS: a clinical, stage, and age-matched analysis[J]. J Clin Oncol, 2018, 36(6-suppl):245-245. RUDEN M, OLIVARES C, FAKHOURY M Q, et al. Prostate cancer presentation, treatment selection, and outcomes among men with HIV/AIDS: a clinical, stage, and age-matched analysis[J]. J Clin Oncol, 2018, 36(6-suppl):245-245.
14、 李爱新,王莉琳,汪雯,等. 艾滋病合并新型隐球菌性脑膜炎81例临床特征分析[J]. 中华传染病杂志,2019,37(11):656-660. 李爱新,王莉琳,汪雯,等. 艾滋病合并新型隐球菌性脑膜炎81例临床特征分析[J]. 中华传染病杂志,2019,37(11):656-660.
15、 贾春辉,王磊,荆凡辉,等. 艾滋病合并巨细胞病毒感染48例临床分析及T淋巴细胞亚群特点[J]. 中华内科杂志,2019,58(3):191-197. 贾春辉,王磊,荆凡辉,等. 艾滋病合并巨细胞病毒感染48例临床分析及T淋巴细胞亚群特点[J]. 中华内科杂志,2019,58(3):191-197.
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