您的位置: 首页 > 2019年5月 第50卷 第3期 > 文字全文
2023年7月 第38卷 第7期11
目录

FRAX®评估广州社区中老年人群骨折风险的回顾性研究

A retrospective study of FRAX in predicting the fracture risk of senile people in Guangzhou community

来源期刊: 广州医药 | - 发布时间:2021-12-17 收稿时间:2025/11/13 17:27:32 阅读量:21
作者:
关键词:
骨质疏松症骨折FRAX危险因素
OsteoporosisFractureFracture risk assessment tool FRAXRisk factors
DOI:
收稿时间:
2019-02-17 
修订日期:
 
接收日期:
 
引用总数:
0  
目的 应用FRAX®工具评估广州社区中老年人发生骨质疏松性骨折的风险。方法 回顾性研究1 140例广州社区中老年人的临床资料,应用FRAX®工具计算未来10年发生主要骨质疏松性骨折及髋部骨折的风险,分析不同危险因素与骨折风险的关系。结果 广州社区中老年人群10年内发生主要骨质疏松性骨折概率为(4.2±3.6)%,髋部骨折概率为(1.3±2.4)%。主要骨质疏松性骨折风险及髋部骨折风险、OSTA值均随着年龄增长而增加。多因素回归分析结果显示: 年龄、性别、既往骨折、继发性骨质疏松、股骨颈T值、跌倒对主要部位骨折及髋部骨折风险具有独立性预测意义。结论 FRAX®工具可用于评估广州社区中老年人骨质疏松性骨折风险,建议在社区中老年人健康体检时应用FRAX®工具进行骨折风险评估。
Objective To predict the osteoporotic fracture risk in senile people in Guangzhou communities by FRAX,the fracture risk assessment tool published by WHO. Methods Clinical data of 1140 cases were collected for the retrospective analysis. The FRAX tool was uesed to calculate the 10-year probability of a major osteoporotic and hip fracture.The relationship between different risk factors and the fracture risk predicted by FRAX was analyzed. Results The 10-year probability of major osteoporotic fractures was (4.2±3.6)%, and the 10-year probability of hip fractures was (1.3±2.4)%.The 10-year probability of the major osteoporotic and hip fracture increased with age.Multivariate regression analysis showed that age,gender,previous fracture,secondary osteoporosis,T-score of femoral neck BMD and fall were independent predictors of the 10-year probability of major osteoporotic fracture and hip fracture. Conclusion The FRAX tool may be effectively applied to assess the fracture risk of senile population in Guangzhou communities.We recommedated that FRAX-tool should be included in routine health check-up.
1、 US PREVENTIVE SERVICES TASK FORCE. Screening for osteoporosis to prevent fractures: us preventive services task force recommendation statement [J]. JAMA, 2018, 319 (24): 2521-2531. US PREVENTIVE SERVICES TASK FORCE. Screening for osteoporosis to prevent fractures: us preventive services task force recommendation statement [J]. JAMA, 2018, 319 (24): 2521-2531.
2、 中华医学会骨质疏松和骨矿盐疾病分会,原发性骨质疏松症诊疗指南(2017) [J]. 中华骨质疏松和骨矿盐疾病杂志,2017,10(5): 413-444. 中华医学会骨质疏松和骨矿盐疾病分会,原发性骨质疏松症诊疗指南(2017) [J]. 中华骨质疏松和骨矿盐疾病杂志,2017,10(5): 413-444.
3、 LI F,ECKSTROM E,HARMER P, et al. Exercise and fall prevention: narrowing the reserch-to-practice gap and enhancing integration of clinical and community practice [J]. J Am Geriatr Soc,2016,64(2): 425-431. LI F,ECKSTROM E,HARMER P, et al. Exercise and fall prevention: narrowing the reserch-to-practice gap and enhancing integration of clinical and community practice [J]. J Am Geriatr Soc,2016,64(2): 425-431.
4、 ZHANG Z W,QU Y N,SHENG Z F,et al. How to decide intervention thresholds based on FRAX in central south Chinese postmenopausal women [J]. Endocrine,2014,45(2): 195-197. ZHANG Z W,QU Y N,SHENG Z F,et al. How to decide intervention thresholds based on FRAX in central south Chinese postmenopausal women [J]. Endocrine,2014,45(2): 195-197.
5、 EUGENE V,MCCLOSKEY, NICHOLAS C,et al. FRAX updates 2016 [J]. Curr Opin Rheumatol, 2016,28(4): 433-441. EUGENE V,MCCLOSKEY, NICHOLAS C,et al. FRAX updates 2016 [J]. Curr Opin Rheumatol, 2016,28(4): 433-441.
6、 常帅,张智海,刘忠厚,等. FRAX评估北京地区中老年人群骨折风险的回顾性研究 [J]. 中国骨质疏松和骨矿盐疾病杂志,2016,22(4): 447-451. 常帅,张智海,刘忠厚,等. FRAX评估北京地区中老年人群骨折风险的回顾性研究 [J]. 中国骨质疏松和骨矿盐疾病杂志,2016,22(4): 447-451.
7、 崔羽, 滕斌, 程天一,等. 上海市社区老年人骨质疏松性骨折的风险评估 [J]. 中国骨质疏松杂志,2016,22(7): 824-827. 崔羽, 滕斌, 程天一,等. 上海市社区老年人骨质疏松性骨折的风险评估 [J]. 中国骨质疏松杂志,2016,22(7): 824-827.
8、 FUJIWAN S, NAKAMURA T, ORIMO H,et al. Development and application of a Japanese model of the WHO fracture risk assessment tool(FRAX) [J]. Osteoporos Int,2008,9(4): 429-435. FUJIWAN S, NAKAMURA T, ORIMO H,et al. Development and application of a Japanese model of the WHO fracture risk assessment tool(FRAX) [J]. Osteoporos Int,2008,9(4): 429-435.
9、 DAWSON G B, TOSTESON A N, MELTON III L J,et al. Implications of absolute fracture risk assessment for osteoporosis practice guidelines in the USA [J]. Osteoporos Int,2008,19(4): 449-458. DAWSON G B, TOSTESON A N, MELTON III L J,et al. Implications of absolute fracture risk assessment for osteoporosis practice guidelines in the USA [J]. Osteoporos Int,2008,19(4): 449-458.
10、 KANIS J A, MC CLOSKEY E V, JOHANSSON H,et a1.Case finding for the management of osteoporosis with FRAX-assessment and intervention thresholds for the UK [J]. Osteoporos Int,2008,19(10): 1395-1408. KANIS J A, MC CLOSKEY E V, JOHANSSON H,et a1.Case finding for the management of osteoporosis with FRAX-assessment and intervention thresholds for the UK [J]. Osteoporos Int,2008,19(10): 1395-1408.
11、 中华医学会骨质疏松和骨矿盐疾病分会,原发性骨质疏松症诊治指南(2011年) [J]. 中华骨质疏松和骨矿盐疾病杂志,2011,4(1): 2-17. 中华医学会骨质疏松和骨矿盐疾病分会,原发性骨质疏松症诊治指南(2011年) [J]. 中华骨质疏松和骨矿盐疾病杂志,2011,4(1): 2-17.
12、 KAINS J A. Assessment of osteoporosis at the primary health-care level [R]. WHO Collaborating Center,UK.University of Sheffield, 2008. KAINS J A. Assessment of osteoporosis at the primary health-care level [R]. WHO Collaborating Center,UK.University of Sheffield, 2008.
13、 SI L, WINZENBERG T M, JIANG Q, et al. Projection of osteoporosis-related fractures and costs in China: 2010-2050 [J]. Osteoporos Int,2015,26(7): 1929-1937. SI L, WINZENBERG T M, JIANG Q, et al. Projection of osteoporosis-related fractures and costs in China: 2010-2050 [J]. Osteoporos Int,2015,26(7): 1929-1937.
14、 中华医学会骨质疏松和骨矿盐疾病分会, 中华医学会骨科学分会骨质疏松学组.骨质疏松性骨折患者抗骨质疏松治疗与管理专家共识 [J]. 中华骨质疏松和骨矿盐疾病杂志,2015,8(3): 189-195. 中华医学会骨质疏松和骨矿盐疾病分会, 中华医学会骨科学分会骨质疏松学组.骨质疏松性骨折患者抗骨质疏松治疗与管理专家共识 [J]. 中华骨质疏松和骨矿盐疾病杂志,2015,8(3): 189-195.
15、 COSMAN F I, de BEUR S J, LEBOFF M S, et al. Clinician's Guide to Prevention and Treatment of Osteoporosis [J]. Osteoporos Int,2014,25(10): 2359-2381. COSMAN F I, de BEUR S J, LEBOFF M S, et al. Clinician's Guide to Prevention and Treatment of Osteoporosis [J]. Osteoporos Int,2014,25(10): 2359-2381.
16、 中华人民共和国国家统计局.中国统计年鉴 [M]. 北京: 中国统计出版社,2015. 中华人民共和国国家统计局.中国统计年鉴 [M]. 北京: 中国统计出版社,2015.
17、 KAINS J A, MC CLOSKEY E V, JOHANSSON H, et al. European guidance for the diagnosis and management of osteoporosis in postmenopausal women [J]. Osteoporos Int,2013,24(1): 23-57. KAINS J A, MC CLOSKEY E V, JOHANSSON H, et al. European guidance for the diagnosis and management of osteoporosis in postmenopausal women [J]. Osteoporos Int,2013,24(1): 23-57.
上一篇
下一篇
出版者信息








《广州医药》公众号
目录