Objective To explore the nursing in reducing risk of patients' pre-hospital condition recognition. Methods 106 patients were treated by emergency care in pre-hospital period. Among all patients a simple clinical scoring condition assessment(SCS) were given to 53 patients, who were in control group, and other 53 cases were treated by modified early warning score model (MEWS), who were in observation group. Emergency care was given to all critical patients in pre-hospital period. Then we compared the effects. Results The pre-hospital consumed time was significantly less, transportation survival rate and satisfaction rate of patients were both higher, complication rate was lower in observation group than control group(P＜0.05). The AUC was 0.861(P＜0. 001) of MEWS for evaluating survival rate after 28 days by the ROC curve analysis. The score of cutoff value was 6.98, sensitivity was 87.2%, specificity was 91.6%, which were all better than SCS. Conclusion Early warning score model may decrease the risk of condition recognition in pre-hospital period, improve rescue success rate and nursing quality, providing a better sensitivity and accuracy for prognosis evaluation.