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超声造影评价不同厚度颈动脉斑块内新生血管的临床研究

Evaluation of neovascularization in carotid arteries with different thickness by contrast enhanced ultrasound

来源期刊: 广州医药 | 46-49 发布时间:2021-12-01 收稿时间:2025/11/13 17:23:31 阅读量:16
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关键词:
超声造影超声检查颈动脉粥样硬化新生血管
Contrast enhanced ultrasoundUltrasonographyCarotid atherosclerotic plaqueNeovascularization
DOI:
10.3969/j.issn.1000-8535.2018.02.012
收稿时间:
2017-11-25 
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引用总数:
0  
目的 通过超声造影成像技术( CEUS)观察颈动脉斑块内新生血管的情况,探讨颈动脉斑块的厚度与新生血管的关系。方法 选择颈动脉粥样硬化患者40例,经常规超声确诊存在斑块,共64个,应用CEUS成像技术检测斑块内新生血管情况。结果 不同厚度的颈动脉斑块的增强强度与斑块厚度成正相关(r=0.897 6,P=0.000 0)。结论 超声造影成像技术可以在常规超声的基础上通过检测斑块内的新生血管,进而判断斑块的性质,提供更多有用的信息进一步评估颈动脉斑块内新生血管增强强度与斑块厚度存在线性正相关性。
Objective To evaluate the neovascularization in carotid plaques by gray-scale harmonic contrast echocardiography (CEUS), and to investigate the relationship between the thickness of carotid artery plaque and the neovascularization.Methods 40 patients with carotid atherosclerosis were selected, and 64 plaques were diagnosed by regular ultrasound. The neovascularization in plaques was detected by CEUS imaging technique.Results The enhanced strength of carotid plaques with different thickness was positively correlated with plaque thickness (r=0.8976,P=0.0000).Conclusion Ultrasound contrast imaging can detect angiogenesis within the plaque based on conventional ultrasound, and then determine the nature of the plaque. More useful information is provided to further evaluate the linear positive correlation between the intensity of neovascularization and the thickness of plaque in carotid plaque.
1、 NOLZ R, WIBMER A, BEITZKE D, et al. Carotid artery stenting and follow up: Value of 64-MSCT angiography as complementary imaging method to color coded duplex sonography[J]. Eur J Radiol, 2012,81(1):89-94. NOLZ R, WIBMER A, BEITZKE D, et al. Carotid artery stenting and follow up: Value of 64-MSCT angiography as complementary imaging method to color coded duplex sonography[J]. Eur J Radiol, 2012,81(1):89-94.
2、 ATKINSON T, LINDNER J R. Ultrasound molecular imaging of endothelial cell activation and damage in atherosclerosis [J]. Springer,2015,11(7): 39-63. ATKINSON T, LINDNER J R. Ultrasound molecular imaging of endothelial cell activation and damage in atherosclerosis [J]. Springer,2015,11(7): 39-63.
3、 PALTIEL H J, PADUA H M, GARGOLLO P C, et al. Contrast-enhanced, real time volumetric ultrasound imaging of tissue perfusion: Preliminary results in a rabbit model of testicular torsion[J]. Phys Med Biol, 2011,56(7):2183-2197.  PALTIEL H J, PADUA H M, GARGOLLO P C, et al. Contrast-enhanced, real time volumetric ultrasound imaging of tissue perfusion: Preliminary results in a rabbit model of testicular torsion[J]. Phys Med Biol, 2011,56(7):2183-2197. 
4、 HWANG D S, SHIN E S, KIM S J, et al. Early differential changes in coronary plaque composition according to plaque stability following statin initiation in acute coronary syndrome: Classification and analysis by intravascular ultrasound-virtual histology[J]. Yonsei Med J, 2013,54(2):336-334. HWANG D S, SHIN E S, KIM S J, et al. Early differential changes in coronary plaque composition according to plaque stability following statin initiation in acute coronary syndrome: Classification and analysis by intravascular ultrasound-virtual histology[J]. Yonsei Med J, 2013,54(2):336-334.
5、 MOZAFFARIAN D,BENJAMIN E J,GO A S,et al. Heart disease and stroke statistics-2015 update: a report from the American Heart Association[J]. Circulation,2015,131( 4): 29. MOZAFFARIAN D,BENJAMIN E J,GO A S,et al. Heart disease and stroke statistics-2015 update: a report from the American Heart Association[J]. Circulation,2015,131( 4): 29.
6、 魏立亚,何文,张红霞,等.颈动脉硬化斑块内新生血管的超声造影研究 [J/0L]. 中华医学超声杂志 (电子版),2009,6(66):1095-1102. 魏立亚,何文,张红霞,等.颈动脉硬化斑块内新生血管的超声造影研究 [J/0L]. 中华医学超声杂志 (电子版),2009,6(66):1095-1102.
7、 GRAY-WEALE A C, GRAHAM J C, BURNETT J R, et al. Carotid artery atheroma:coparison of preoperative B-mode ultrasound tomy specimen pathology[J]. Cardiovasc Srug(Torino),1988,29(6):676-681. GRAY-WEALE A C, GRAHAM J C, BURNETT J R, et al. Carotid artery atheroma:coparison of preoperative B-mode ultrasound tomy specimen pathology[J]. Cardiovasc Srug(Torino),1988,29(6):676-681.
8、 薛红元, 叶玉泉, 高丽,等. 应用超声造影技术对不同厚度颈动脉斑块内新生血管的评价[J]. 中国超声医学杂志, 2016, 32(6):491-493. 薛红元, 叶玉泉, 高丽,等. 应用超声造影技术对不同厚度颈动脉斑块内新生血管的评价[J]. 中国超声医学杂志, 2016, 32(6):491-493.
9、 李超伦,何婉媛,郭大乔,等. 超声造影颈动脉斑块内增强强度与动脉狭窄程度的关系[J]. 中国超声医学杂志,2013,29(2):106-109. 李超伦,何婉媛,郭大乔,等. 超声造影颈动脉斑块内增强强度与动脉狭窄程度的关系[J]. 中国超声医学杂志,2013,29(2):106-109.
10、 金玉明,洪桂荣.颈动脉斑块微血管超声成像[J].中国超声医学杂志,2015,31(10):948-949. 金玉明,洪桂荣.颈动脉斑块微血管超声成像[J].中国超声医学杂志,2015,31(10):948-949.
11、 HELLINGS W E, PEETERS W, MOLL F L, et al. Compositon of carotidathersoclerotic plaque is associated with cardiovascular outcome:aprognostic study[J]. Circulation,2010,121(17):1941-1950.  HELLINGS W E, PEETERS W, MOLL F L, et al. Compositon of carotidathersoclerotic plaque is associated with cardiovascular outcome:aprognostic study[J]. Circulation,2010,121(17):1941-1950. 
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