Objective According to the physiological characteristics of postpartum breast, through the combined treatment of traditional Chinese medicine and nursing for delactation,and to observe the effects. Methods A total of 57 women who wanted for delactation, were selected and randomly divided into two groups, there are 30 cases in the treatment group and 27 cases in the control group, the treatment group were treated with traditional Chinese medicine and nursing, while the control group used oral bromocriptine for delactation. Results The treatment group is better than the control group, the incidence of mastitis and breast swelling in treatment group is lower than the control group, and there was no adverse reaction. Conclusion The treatment of delactation with combined treatment of traditional chinese medicine and nursing is safe and effective, it can reduce suffering of women and prevent the occurrence of mastitis.