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脑梗塞与雌激素及高同型半胱氨酸血症之间的相关性研究

Correlation Study between Cerebral Infarction and Estrogen and Hyperhomocysteinemia

来源期刊: 广州医药 | 88-89 发布时间:2021-11-30 收稿时间:2025/11/13 16:45:41 阅读量:17
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关键词:
脑梗塞雌激素高同型半胱氨酸血症相关性
DOI:
10.3969/j.issn.1000-8535.2015.04.030
收稿时间:
2015-03-21 
修订日期:
 
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引用总数:
0  
目的 探讨脑梗塞与雌激素及高同型半胱氨酸血症之间的相关性。方法 纳入我院2013年1月—2014年11月确诊为脑梗塞的患者100例,正常对照的健康体检者100例,比较两组患者的血浆高同型半胱氨酸和雌激素水平。结果 脑梗死患者的血浆同型半胱氨酸水平高于正常组,两组比较差异有统计学意义(P<0.05);高同型半胱氨酸血症脑梗塞组为72例,正常组为18例,两组比较差异有统计学意义(P<0.05);同型半胱氨酸的阳性率男性为92%,女性为44%,男性患者高于女性,(P<0.05);脑梗塞组雌激素水平降低,脑梗塞和雌激素水平呈负相关(P<0.05),有糖尿病和酗酒的患者E2水平低于无糖尿病和酗酒的E2水平,差异有统计学意义(P<0.05)。结论 急性脑梗塞患者同型半胱氨酸水平高于正常组,雌激素水平低于正常组,高同型半胱氨酸血症是脑梗死的重要危险因素,雌激素为脑梗塞患者的保护性因素。
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