您的位置: 首页 > 2015年9月 第46卷 第5期 > 文字全文
2023年7月 第38卷 第7期11
目录

RD105缺失基因检测法用于青海省北京/W系结核分枝杆菌鉴定

Identification of Beijing/W lineage mycobacterium tuberculosis in Qinghai province by using an RD105 deletion test

来源期刊: 广州医药 | 11-14 发布时间:2021-11-30 收稿时间:2025/11/13 16:41:03 阅读量:6
作者:
关键词:
结核分支杆菌RD105北京/W系结核分枝杆菌
Mycobacterium tuberculosisRD105Beijing/W lineage Mycobacterium tuberculosis
DOI:
10.3969/j.issn.1000-8535.2015.05.004
收稿时间:
2015-05-06 
修订日期:
 
接收日期:
 
引用总数:
0  
目的 了解青海省北京/W系结核分枝杆菌分布特征。方法 收集青海地区结核分支杆菌临床分离株,采用RD105缺失基因检测鉴定北京/W系结核分枝杆菌。结果 共收集237株结核分枝杆菌临床分离株,采用RD105缺失基因检测鉴定北京/W系结核分枝杆菌220株,占92.8%,非北京/W结核分枝杆菌,共17株,占7.2%。北京/W系结核分枝杆菌在青海地区性别与民族分布差异没有统计学意义(P>0.05)。结论 北京/W结核分枝杆菌为青海地区流行菌株,在人群易于发生感染和传播。
Objective To ascertain the epidemiological characteristics of Beijing/W lineage Mycobacterium tuberculosis in Qinghai Province. Methods M. tuberculosis clinical isolates were collected and identified with an RD105 deletion test.Statistical analysis was performed by using the test. Results Totally, 237 clinical isolates of M. tuberculosis were collected in which 220 strains (92.8%) belonged to the Beijing/W lineage of M. tuberculosis while 17strains (7.2%) belonged to the non-Beijing/W lineage of M. tuberculosis according to the RD105 deletion test. There were no significant differences in the distribution of Beijing/W lineage of M. tuberculosis in the gender and nationality (P>0.05). Conclusion Beijing/W lineage of M. tuberculosis were prevalent in Qinghai province and prone to having infection and transmission in the crowd.
1、 高铁杰, 李卫民, 刘毅, 等. 北京昌平区北京/W系结核分枝杆菌的流行特征[J]. 郑州大学学报(医学版),2010,45(1):47-50. 高铁杰, 李卫民, 刘毅, 等. 北京昌平区北京/W系结核分枝杆菌的流行特征[J]. 郑州大学学报(医学版),2010,45(1):47-50.
2、 Wada T, Iwamoto T. Allelic diversity of variable number of tandem repeats providesphylogenetic clues regarding the Mycobacterium tuberculosis Beijing family [J]. Infection Genetics and Evolution, 2009, 9(5): 921-926. Wada T, Iwamoto T. Allelic diversity of variable number of tandem repeats providesphylogenetic clues regarding the Mycobacterium tuberculosis Beijing family [J]. Infection Genetics and Evolution, 2009, 9(5): 921-926.
3、 Wang J, Liu Y, Zhang CL, et al. Genotypes and characteristics of clustering and drug susceptibility of Mycobacterium tuberculosis isolates collected in Heilongjiang Province, China[J]. Journal of clinical microbiology, 2011,49(4): 1354-1362. Wang J, Liu Y, Zhang CL, et al. Genotypes and characteristics of clustering and drug susceptibility of Mycobacterium tuberculosis isolates collected in Heilongjiang Province, China[J]. Journal of clinical microbiology, 2011,49(4): 1354-1362.
4、 赵秀芹,董海燕,刘志广,等. 中国部分地区结核分枝杆菌北京基因型菌株分布初步分析[J]. 实用预防医学, 2012(5):662-664. 赵秀芹,董海燕,刘志广,等. 中国部分地区结核分枝杆菌北京基因型菌株分布初步分析[J]. 实用预防医学, 2012(5):662-664.
5、 吴长东,米利古,龚天美,等. RD105缺失基因检测法用于结核分枝杆菌新疆“北京家族”临床分离株的鉴定[J]. 2010,5(3):161-167. 吴长东,米利古,龚天美,等. RD105缺失基因检测法用于结核分枝杆菌新疆“北京家族”临床分离株的鉴定[J]. 2010,5(3):161-167.
6、 Kong Y, Cave MD, Zhang L, et al. Population-Based Study of Deletions in Five Different Genomic Regions of Mycobacterium tuberculosis and Possible Clinical Relevance of the Deletions[J]. J Clin Microbiol, 2006,44(11):3940-3946. Kong Y, Cave MD, Zhang L, et al. Population-Based Study of Deletions in Five Different Genomic Regions of Mycobacterium tuberculosis and Possible Clinical Relevance of the Deletions[J]. J Clin Microbiol, 2006,44(11):3940-3946.
7、 Wang J, Liu Y, Zhang CL, et al. Genotypes and characteristics of clustering and drug susceptibility of Mycobacterium tuberculosis isolates collected in Heilongjiang Province, China[J]. J Clin Microbiol, 2011,49(4):1354-1362. Wang J, Liu Y, Zhang CL, et al. Genotypes and characteristics of clustering and drug susceptibility of Mycobacterium tuberculosis isolates collected in Heilongjiang Province, China[J]. J Clin Microbiol, 2011,49(4):1354-1362.
8、 Dong H, Shi L, Zhao X, et al. Genetic diversity of Mycobacterium tuberculosis isolates from Tibetans in Tibet, China[J]. PLoS One, 2012,7(3):e33904. Dong H, Shi L, Zhao X, et al. Genetic diversity of Mycobacterium tuberculosis isolates from Tibetans in Tibet, China[J]. PLoS One, 2012,7(3):e33904.
9、 Chai LQ, Li WM, Li L, et al. Study on the genotype of Mycobacterium tuberculosis isolates from hospitals in Tianjin[J]. Zhonghua Liu Xing Bing Xue Za Zhi, 2007,28(8):785-788. Chai LQ, Li WM, Li L, et al. Study on the genotype of Mycobacterium tuberculosis isolates from hospitals in Tianjin[J]. Zhonghua Liu Xing Bing Xue Za Zhi, 2007,28(8):785-788.
10、 王兆芬,李斌,马永成,等. 青海省结核分枝杆菌的间隔寡核苷酸分型研究[J]. 中华预防医学杂志, 2015,49(6):117-119. 王兆芬,李斌,马永成,等. 青海省结核分枝杆菌的间隔寡核苷酸分型研究[J]. 中华预防医学杂志, 2015,49(6):117-119.
11、 王黎霞,成诗明,陈明亭,等. 2010年全国第五次结核病流行病学抽样调查报告[J]. 中国防痨杂志, 2012(8):485-508. 王黎霞,成诗明,陈明亭,等. 2010年全国第五次结核病流行病学抽样调查报告[J]. 中国防痨杂志, 2012(8):485-508.
上一篇
下一篇
出版者信息








《广州医药》公众号
目录