儿童注意缺陷多动障碍共患病研究热点可视化分析

doi:10.20223/j.cnki.1000-8535.2025.09.007

摘要/Abstract

摘要： 目的利用可视化软件CiteSpace分析近20年儿童注意缺陷多动障碍（ADHD）及其共患病的相关文献,得出该领域的研究现状和发展趋势,为儿童注意缺陷多动障碍及其共患病的研究和诊疗提供参考。方法检索2004—2024年发表在中国知网、维普、万方数据库关于儿童注意缺陷多动障碍及其共患病的相关文献,运用CiteSpace软件对纳入文献进行可视化分析,对来源、机构、发文量、作者、关键词绘制科学知识图谱。结果共纳入383个机构、500个作者、235种期刊、577篇有效文献。自2012年发文量总体上呈波动上升趋势;在发文来源中,《中国儿童保健杂志》以47篇居首;研究机构以北京大学精神卫生研究所为代表;王玉凤作者发文21篇为最多;ADHD患儿的主要共患病为抽动障碍、癫痫、对立违抗障碍、学习障碍;主要治疗药物为托莫西汀;主要影响患儿的执行功能。ADHD患儿共患病研究分为3个阶段,第一阶段为2004—2009年,研究对象主要为品行障碍、对立违抗障碍、学习障碍、焦虑障碍,主要研究内容为患儿的脑损伤与基因;第二阶段为2009—2017年,重视研究患儿的心理问题,如焦虑、抑郁,也重视患儿的生活及家庭环境;第三阶段为2017—2024年,重点研究托莫西汀、阿立哌唑等药物,并重视ADHD共患癫痫的研究。结论目前对ADHD共患病的研究仍较为局限,主要集中研究共患抽动障碍、对立违抗障碍、癫痫,未来应重视研究其他共患病,进一步探索更好的诊治方法。

关键词: 儿童, 注意缺陷多动障碍, 共患病, 可视化分析, CiteSpace

Abstract: Objective To analyze the literature on attention deficit hyperactivity disorder（ADHD）and its comorbidities in children in the past 20 years by using the visualization software CiteSpace,and to obtain the research status and development trend of this field,so as to provide reference for the research,diagnosis and treatment of ADHD and its comorbidities in children. Methods The relevant literature on ADHD and its comorbidities in children published in CNKI,VIP and Wanfang data bases from 2004 to 2024 was searched,and the included literature was visually analyzed by CiteSpace 6. 2R6 software,and the scientific knowledge graph was drawn by the source,institution,number of publications,authors and keywords. Results A total of 383 institutions,500 authors,235 journals,and 577 valid articles were included. Since 2012,the number of published documents has fluctuated and increased. Among the sources of publication,the Chinese Journal of Child Health ranked first with 47 articles. The research institutions were represented by the Institute of Mental Health of Peking University. Wang Yufeng was the most prolific author with 21 articles. The main comorbidities of ADHD children were tic disorder,epilepsy,oppositional defiant disorder and learning disorder. The main treatment drug was tomoxetine. It mainly affects the executive function of the children. The study on comorbidity in children with ADHD was divided into three stages. The first stage was from 2004 to 2009. The research objects mainly included conduct disorder,oppositional defiant disorder,learning disorder and anxiety disorder,and the main research content was brain injury and genes in children. The second stage,from 2009 to 2017,focused on the psychological problems of children,such as anxiety and depression,and also paid attention to the life and family environment of children. The third stage was 2017-2024,focusing on tomoxetine,aripiprazole and other drugs,and paying attention to the study of ADHD co-induced epilepsy. Conclusions The current research on ADHD and its comorbidities is still limited,and its pathogenesis should be explored in the future,so as to quickly and accurately identify comorbidities and further study better treatments.

Key words: children, attention deficit hyperactivity disorder, comorbidities, visual analytics, CiteSpace

乔荣, 卢宣君, 刘馨雅, 孙梦洁, 李亚平. 儿童注意缺陷多动障碍共患病研究热点可视化分析[J]. 广州医药, 2025, 56(9): 1208-1216.

QIAO Rong, LU Xuanjun, LIU Xinya, SUN Mengjie, LI Yaping. Visual analysis of research hotspots on comorbidity of attention deficit hyperactivity disorder in children[J]. Guangzhou Medical Journal, 2025, 56(9): 1208-1216.

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