隔药壮灸神阙穴治疗女性黄褐斑临床疗效观察及其对血清性激素水平影响研究

doi:10.3969/j.issn.1000-8535.2015.04.008

广州医药 ›› 2015, Vol. 46 ›› Issue (4): 26-28.DOI: 10.3969/j.issn.1000-8535.2015.04.008

隔药壮灸神阙穴治疗女性黄褐斑临床疗效观察及其对血清性激素水平影响研究

李璟蓉¹, 张新斐², 欧阳群², 王建琴¹

1 广州市南沙中心医院皮肤科(广州 511457)
2 广东三九脑科医院康复中心(广州 510510)

收稿日期:2015-02-28 发布日期:2021-11-30
通讯作者: 李璟蓉,E-mail:lii661018@126.com
基金资助:
广州市中医药科技项目(20132A011005)

Clinical efficacy on female chloasma treated with acupuncture of Zhuang minority medicine at Shengque xue and detection of serum sex hormone levels

Li Jingrong, Zhang Xinfei, Ouyang Qun, Wang Jianqin

Department of Dermatology, Guangzhou Nansha Central Hospital, Guangzhou 511457,China;
Department of Rehabilitation Centre, Guangdong 999 Brain Hospital, Guangzhou 510510, China

Received:2015-02-28 Published:2021-11-30

摘要/Abstract

摘要： 目的观察隔药壮灸神阙穴治疗女性黄褐斑的临床疗效及对血清性激素水平的影响。方法将72例患者随机分为2组,治疗组38例和对照组34例,治疗组予隔药壮灸神阙穴治疗,对照组予口服维生素C、维生素E治疗,10次为1个疗程,第2、4、6疗程末观察疗效,治疗前后测定月经第2～3天血清雌二醇(E2)、孕酮(P)、泌乳素(PRL)、卵泡刺激素(FSH)、黄体生成素(LH)、睾酮(T)水平。结果第6疗程末治疗组总有效率为83.33％,对照组总有效率30.30%,治疗组疗效优于对照组(P＜0.05),治疗组治疗前后E2、LH下降水平有统计学意义(P＜0.05)。对照组治疗前后E2、P、PRL、FSH、LH、T水平变化不明显(P＞0.05)。治疗后2组E2、LH比较,差异有统计学意义(P＜0.05)。结论隔药壮灸神阙穴治疗女性黄褐斑临床疗效较好,可能通过调节性激素而起到治疗作用。

关键词: 黄褐斑, 女性, 隔药壮灸, 神阙穴, 性激素

Abstract: Objective To observe the clinical efficacy on female chloasma treated with acupuncture of Zhuang minority medicine at Shengque xue and its influence on sex hormone levels. Methods 72 cases were divided randomly into a treatment group(38 cases) and a control group(34 cases). In treatment group, acupuncture of Zhuang minority medicine at Shengque xue was applied. In control group, oral administration of vitamin C and vitamin E were given. The cases of treatment group were treated ten times as one session. At the end of 2,4,6 treatment session efficacy were analyzed respectively. The levels of serum estradiol(E2), progesterone(P), prolactin(PRL), follicule stimulating hormone(FSH), luteinizing hormone(LH) and testosterone(T) were detected on day 2-3 of menstruation. Results At the end of 6 treatment session the total effective rate was 83.33％ in treatment group and was 30.30% in control group, the efficacy in treatment group were superior to that in control group, with significant difference(P＜0.05). In treatment group, the levels of LH and E2 after treatment were lower as compared with those before treatment(P＜0.05). In control group, there were no obvious changes in E2,P, PRL, FSH, LH and T before and after treatment(P＞0.05). The levels of LH and E2 after treatment were significantly different in comparison of two groups(P＜0.05). Conclusion Acupuncture of Zhuang minority medicine at Shengque xue achieves a definite efficacy on female chloasma in clinic and its pharmacological mechanism may be relevant with its regulation on sex hormone levels for the patients.

Key words: Chloasma, female, Acupuncture of Zhuang minority medicine, Shenque Xue, Sex hormones

李璟蓉, 张新斐, 欧阳群, 王建琴. 隔药壮灸神阙穴治疗女性黄褐斑临床疗效观察及其对血清性激素水平影响研究[J]. 广州医药, 2015, 46(4): 26-28.

Li Jingrong, Zhang Xinfei, Ouyang Qun, Wang Jianqin. Clinical efficacy on female chloasma treated with acupuncture of Zhuang minority medicine at Shengque xue and detection of serum sex hormone levels[J]. Guangzhou Medical Journal, 2015, 46(4): 26-28.

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隔药壮灸神阙穴治疗女性黄褐斑临床疗效观察及其对血清性激素水平影响研究

Clinical efficacy on female chloasma treated with acupuncture of Zhuang minority medicine at Shengque xue and detection of serum sex hormone levels

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