广州医药 ›› 2016, Vol. 47 ›› Issue (3): 46-48.DOI: 10.3969/j.issn.1000-8535.2016.03.017

• 论著 • 上一篇    下一篇

绝经期后女性血清铁蛋白水平与代谢综合征的相关性

赖菲菲1, 林潭发1, 林占1, 王吓勇2   

  1. 1 广东省惠州市中心人民医院内分泌科(惠州 516001)
    2 惠州市口腔医院(惠州 516001)
  • 收稿日期:2016-01-17 出版日期:2016-05-20 发布日期:2021-11-30
  • 基金资助:
    惠州市科技计划项目(2015Y016)

Correlation between serum ferritin level and metabolic syndrome in postmenopausal women

Lai Feifei, Lin Tanfa, Lin Zhan, Wang Xiayong   

  1. Lai Feifei, Lin Tanfa, Lin Zhan. Department of Endocrinology, People's Hospital of Huizhou City Center, Huizhou 516001, China
    Wang Xiayong. Huizhou Hospital of Stomatology, Huizhou 516001,China
  • Received:2016-01-17 Online:2016-05-20 Published:2021-11-30

摘要: 目的 探讨绝经期后女性血清铁蛋白水平与代谢综合征之间的关系。方法 收集218例确诊为MS的绝经期后女性患者为试验组,对照组为经我院检查健康绝经期后的女性300例,分别测FBG、TC、TG、LDL-C、HDL-C、HbA1C、INS、SF;计算体重指数(BMI)以及测量腰围;测血压;用HOMA稳态模型来评价胰岛素抵抗指数(HOMA-IR)。结果 MS组较非MS组的铁蛋白(SF)值高(P<0.01),SF四分位各组之间比较,FBG、TG、HDL-C,BMI,腰围,收缩压、舒张压有差异(P<0.05或P<0.01),四组间年龄、TC、LDL-C无差异。与SF呈正相关的参数有腰围(P<0.01),舒张压(P<0.01),空腹血糖(P<0.01),胰岛素抵抗指数(P<0.01),负相关的参数为HDL-C(P<0.01)。结论 绝经期后女性的SF水平与MS呈显著相关,其中腰围、舒张压、空腹血糖、HDL-C、胰岛素抵抗指数与血清铁蛋白之间存在较大关联性。

关键词: 绝经期后女性, 血清铁蛋白, 代谢综合征

Abstract: Objective To study the relationship of serum ferritin level with metabolic syndrome in postmenopausal women. Methods 218 postmenopausal women with metabolic syndrome and 300 healthy postmenopausal women were included in this investigation, to detect FBG, TC, TG, LDL- C, HDL-C, HbA1C, INS, SF, calculated body mass index (BMI) and to measure waist circumference, blood pressure; Using HOMA steady-state model to evaluate indexes of insulin resistance (HOMA IR). Results Serum ferritin level was significantly higher in MS group than in the non-MS group(P<0.01). Serum ferritin quarterback was compared between each group, there were differences in FBG, TG, HDL-C,BMI, waist circumference,SBP, DBP(P<0.05 or P<0.01). There were no differences in age, TC, LDL-C. Serum ferritin level was significantly positive correlated with waist circumference (P<0.01), DBP(P<0.01), FBG(P<0.01), insulin resistance index (P<0.01), and negative correlation with HDL-C(P<0.01). Conclusion Serum ferritin level is significantly associated with metabolic syndrome in postmenopausal women. Waist circumference, DBP, FBG, HDL -C, insulin resistance index are closely associated with the serum ferritin.

Key words: Postmenopausal women, Serum ferritin, Metabolic Syndrome