心率变异性与老年患者术后谵妄

doi:10.3969/j.issn.1000-8535.2022.04.001

广州医药 ›› 2022, Vol. 53 ›› Issue (4): 1-4.DOI: 10.3969/j.issn.1000-8535.2022.04.001

• 专家综述 • 下一篇

心率变异性与老年患者术后谵妄

孙家铎¹, 郑彬¹, 徐世元²

1 广州市第一人民医院/华南理工大学附属第二医院麻醉科(广州 510180)
2 南方医科大学珠江医院(广州 510280)

收稿日期:2022-05-26 出版日期:2022-07-20 发布日期:2022-08-03
通讯作者: 郑彬,E-mail:eyzhengbin@scut.edu.cn;徐世元,E-mail: xsy998@smu.edu.cn
作者简介:郑彬,广州市第一人民医院手术麻醉中心副主任,医学博士,主任医师,硕士研究生导师;“广东省杰出青年医学人才”获得者。担任中国中西医结合学会围术期医学分会委员、中国医药教育协会麻醉专业委员会委员、广东省医学会麻醉学分会青年委员会副主任委员、广东省医药教育协会麻醉专业委员会常务委员、广东省药学会麻醉专家委员会常务委员、广东省精准医学应用学会精准麻醉分会常务委员、广州市医学会麻醉学分会秘书以及广州市麻醉质控中心秘书。主要研究方向为围术期神经认知障碍、脑保护。
徐世元,南方医科大学珠江医院麻醉科学术带头人,主任医师,二级教授,博士研究生导师,博士后合作导师;首届珠江医师奖获得者,广东医师奖获得者。任中华医学会麻醉学分会第9~12届全国委员、广东省医学会麻醉学分会第9届主任委员、中国高等教育学会医学高等教育分会麻醉学高等教育学组常务理事、广东省卫计委麻醉质量控制中心副主任委员、广东省广东省医院管理协会麻醉学分会副主任委员;担任《中华麻醉学杂志》、《临床麻醉学杂志》、《国际麻醉学与复苏杂志》以及《中华神经医学杂志》等杂志编委或常务编委。主要研究方向为麻醉药中枢与周围神经毒性机理及防治、阿片类药物急性耐受及痛敏的机制与防治、肌松药药效动力学与肌松监测方法及肌松药作用分子机理、器官血流动力学及氧与能量代谢。
基金资助:
广州市科技计划一般项目(202201010737);2020年广东省医院协会精准及舒适化医疗临床科研基金

Heart rate variability and postoperative delirium in elderly patients

SUN Jiaduo¹, ZHENG Bin¹, XU Shiyuan²

1 Department of Anesthesiology, Guangzhou First People's Hospital, Second Affiliated Hospital of South China University of Technology, Guangzhou 510180, China
2 Zhujiang Hospital of Southern Medical University, Guangzhou 510280, China

Received:2022-05-26 Online:2022-07-20 Published:2022-08-03

摘要/Abstract

摘要： 术后谵妄(POD)指术后严重的注意力及神经认知障碍,其发病率高,且可致多种术后并发症的发生率增加,老年患者为其高危人群之一。相关研究显示:心率变异性(HRV)作为反映自主神经系统(ANS)功能的生物电指标,与老年患者POD的发生相关。本文综述了近年HRV指数与老年患者POD关系的研究,描述了老年患者POD的流行病学规律、ANS功能异常引发POD的可能机制以及HRV与神经认知功能及POD的可能联系,以期为POD的防治提供新的思路。

关键词: 术后谵妄, 心率变异性, 自主神经系统, 老年

Abstract: Postoperative delirium (POD) is a syndrome of severe postoperative attention and neurocognitive impairment, which has a high incidence and can lead to an increased incidence of various postoperative complications. Elderly patients are one of the high-risk groups for POD. Relevant studies have shown that heart rate variability (HRV), as a bioelectrical indicator reflecting the function of the autonomic nervous system (ANS), is associated with the occurrence of POD in elderly patients. This paper reviewed the recent studies on the relationship between HRV index and POD in elderly patients, described the epidemiological regularity of POD in elderly patients, the possible mechanism of POD caused by abnormal ANS function, and the possible connection between HRV and neurocognitive function or POD, in order to provide new evidence for the prevention and treatment of POD.

Key words: postoperative delirium, heart rate variability, autonomic nervous system, elderly

孙家铎, 郑彬, 徐世元. 心率变异性与老年患者术后谵妄[J]. 广州医药, 2022, 53(4): 1-4.

SUN Jiaduo, ZHENG Bin, XU Shiyuan. Heart rate variability and postoperative delirium in elderly patients[J]. Guangzhou Medical Journal, 2022, 53(4): 1-4.

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心率变异性与老年患者术后谵妄

Heart rate variability and postoperative delirium in elderly patients

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