广州医药 ›› 2021, Vol. 52 ›› Issue (3): 28-31.DOI: 10.3969/j.issn.1000-8535.2021.03.005

• 论著 • 上一篇    下一篇

老年急性缺血性脑卒中并发肺部感染的危险因素

陈冬妮1,2, 吴维涛1,2, 肖小华2, 肖孝勇3, 曾鸣2, 崔曼丽2, 杜新1,2   

  1. 1 广州医科大学(广州 510182)
    2 深圳市第二人民医院老年医学科(深圳 518037)
    3 深圳市第二人民医院 急诊科(深圳 518037)
  • 收稿日期:2020-12-03 发布日期:2021-11-24
  • 通讯作者: 杜新,E-mail: duxingz@medmail.com.cn
  • 基金资助:
    深圳市科技创新委员会学科布局项目(JCYJ20180507184647636)

The risk factors of pulmonary infection in elderly patients with acute ischemic stroke

CHEN Dongni1,2 , WU Weitao1,2 , XIAO Xiaohua2, XIAO Xiaoyong3, ZENG Ming2 , CUI Manli2, DU Xin1,2   

  1. 1 Guangzhou Medical Univeristy,Guangzhou 510182,China
    2 Department of Geriatrics, Shenzhen Second People's Hospital,Shenzhen 518037,China
    3 Emergency Department, Shenzhen Second People's Hospital,Shenzhen 518037,China
  • Received:2020-12-03 Published:2021-11-24

摘要: 目的 探讨老年急性缺血性脑卒中并发肺部感染患者的临床特征和相关危险因素。方法 采用回顾性研究方法,选择2017年7月— 2019年10月深圳市第二人民医院神经内科收治的1 113例老年急性缺血性脑卒中患者,其中卒中并发肺部感染患者(108 例)纳入感染组,未并发肺部感染患者(1 005例)纳入对照组。以单因素对比分析两组患者的临床资料,采用 Logistic多因素回归分析方法分析合并肺部感染的高危因素。结果 单因素分析提示两组年龄(尤其是高龄患者)、住院天数、房颤、脑梗死史、慢性肺疾病、吞咽困难、言语不清、意识障碍差异有统计学意义(P <0.05)。多因素 Logistics 回归分析显示,高龄(≥80岁)、住院天数、脑梗死史、吞咽困难、言语不清、意识障碍与老年急性缺血性脑卒中并发肺部感染密切相关。结论 老年急性缺血性脑卒中并发肺部感染的独立危险因素主要是高龄(≥80 岁)、住院天数、脑梗死史、吞咽困难、言语不清、意识障碍,临床应高度重视。

关键词: 老年, 急性缺血性脑卒中, 肺部感染, 临床特征, 危险因素

Abstract: Objective Objective To investigate the clinical characteristics and risk factors of elderly patients with acute ischemic stroke complicated with pulmonary infection. Methods A retrospective study was conducted on 1 113 elderly patients with acute ischemic stroke admitted to the department of neurology, Shenzhen Second People's Hospital from July 2017 to October 2019. Among them, 108 patients with stroke complicated with pulmonary infection were included in the infection group and 1 005 patients without concurrent pulmonary infection were included in the control group. The clinical data of the two groups were analyzed by single factor comparison, and the risk factors for pulmonary infection were analyzed by logistic multiple factor regression analysis. Results Single factor analysis showed there were statistically significant differences between the two groups in age (especially elderly patients), length of stay in hospital, atrial fibrillation, history of cerebral infarction, chronic pulmonary disease, dysphagia, slurred speech, and disturbance of consciousness (P <0.05). Multi-factor logistic regression analysis showed that old age (≥80 years old), length of stay in hospital, history of cerebral infarction, dysphagia, slurred speech, and disturbance of consciousness were closely related to pulmonary infection in elderly patients with acute ischemic stroke. Conclusion The independent risk factors of acute ischemic stroke complicated with pulmonary infection in the elderly mainly include old age (≥80 years old), length of stay in hospital, history of cerebral infarction, dysphagia, slurred speech and disturbance of consciousness, which should be paid more attention to clinically.

Key words: Old age, Acute ischemic stroke, Pulmonary infection, Clinical features, Risk factors