桂枝加芍药汤个体化干预治疗儿童功能性腹痛的临床效果观察

doi:10. 20223 / j. cnki. 1000-8535. 2026. 01. 014

广州医药 ›› 2026, Vol. 57 ›› Issue (1): 95-99.DOI: 10. 20223 / j. cnki. 1000-8535. 2026. 01. 014

桂枝加芍药汤个体化干预治疗儿童功能性腹痛的临床效果观察

胡财喜¹, 车冠德², 欧阳海梅³, 麦华超⁴

1 广东省妇幼保健院急诊科（广东广州 511400）;
2 广东药科大学第一临床医学院（广东广州 510006）;
3 广东省妇幼保健院医务科（广东广州 511400）;
4 广东省妇幼保健院内科（广东广州 511400）

收稿日期:2025-02-28 发布日期:2026-02-03
通讯作者: 麦华超,E-mail：853749142@qq.com
基金资助:
广东省中医药管理局科研项目（20231046）

Clinical effect observation of individualized intervention of Guizhi plus Shaoyao Decoction in the treatment of functional abdominal pain disorders in children

HU Caixi¹, CHE Guande², OUYANG Haimei³, MAI Huachao⁴

1 Emergency Department,Guangdong Women and Children Hospital,Guangzhou 511400,China;
2 The First Clinical Medicine School,Guangdong Pharmaceutical University,Guangzhou 510006,China;
3 Medical Affairs Department,Guangdong Women and Children Hospital,Guangzhou 511400,China;
4 Internal Medicine Department,Guangdong Women and Children Hospital,Guangzhou 511400,China

Received:2025-02-28 Published:2026-02-03

摘要/Abstract

摘要： 目的观察桂枝加芍药汤个体化干预治疗儿童功能性腹痛的临床疗效。方法选取2023年100名在广东省妇幼保健院门急诊就诊确诊为儿童功能性腹痛患儿。100名儿童随机分为两组,益生菌组50名、益生菌+中药个体化干预组50名。连续治疗1周。记录两组患儿卧立位心率、卧立位血压、Rutter 儿童行为量表和中医临床症状的改善情况。结果益生菌+中药个体化干预组患儿治疗后卧立位心率和Rutter儿童行为量表中N行为评分比益生菌组下降,中医临床症状评分的有效率优于益生菌组。结论桂枝加芍药汤个性化干预治疗儿童功能性腹痛疗效显著。

关键词: 桂枝加芍药汤, 自主神经, 儿童功能性腹痛

Abstract: Objective To observe the clinical efficacy of individualized intervention with Guizhi plus Shaoyao Decoction in children with functional abdominal pain disorders（FAPDs）. Methods A total of 100 children diagnosed with FAPDs at the outpatient and emergency departments of Guangdong Women and Children Hospital were selected.These children were randomly divided into two groups：the probiotics group（50 cases）and the probiotics+traditional Chinese medicine individualized intervention group（50 cases）.Both groups received continuous treatment for 1 week.Parameters including supine/upright heart rates,supine/upright blood pressure,Rutter Children's Behavior Questionnaire,and improvements in traditional Chinese clinical symptom scores were recorded. Results The probiotics+traditional Chinese medicine individualized intervention group exhibited significantly greater reductions in supine/upright heart rates and N-behavior scores compared to the probiotics group.The effective rate of Chinese clinical symptom scores was also significantly higher in the individualized intervention group. Conclusions Individualized intervention of Guizhi plus Shaoyao Decoction has a remarkable efficacy in treating FAPDs in children.

Key words: Guizhi plus Shaoyao Decoction, autonomic nerve, functional abdominal pain disorders

胡财喜, 车冠德, 欧阳海梅, 麦华超. 桂枝加芍药汤个体化干预治疗儿童功能性腹痛的临床效果观察[J]. 广州医药, 2026, 57(1): 95-99.

HU Caixi, CHE Guande, OUYANG Haimei, MAI Huachao. Clinical effect observation of individualized intervention of Guizhi plus Shaoyao Decoction in the treatment of functional abdominal pain disorders in children[J]. Guangzhou Medical Journal, 2026, 57(1): 95-99.

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桂枝加芍药汤个体化干预治疗儿童功能性腹痛的临床效果观察

Clinical effect observation of individualized intervention of Guizhi plus Shaoyao Decoction in the treatment of functional abdominal pain disorders in children

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