关键词: 老年营养风险指数, 慢性阻塞性肺疾病急性加重, 死亡

Abstract: Objective To investigate the correlation between elderly nutritional risk index（GNRI）and prognosis of patients with AECOPD. Methods Patients with AECOPD admitted to our hospital from January 2019 to January 2022 were selected and divided into normal nutrition group（GNRI>98）and malnutrition group（GNRI≤98）according to GNRI value．Survival curve and Cox regression were used to evaluate the association between nutritional status and mortality. Results A total of 198 patients with AECOPD were included in this study．According to GNRI scores,90 patients were in the normal nutrition group and 108 were in the malnutrition group,with malnutrition incidence of 54.5%．The Kaplan-Meier curve showed that the cumulative all-cause mortality was higher in the malnutrition group（58.3% vs 35%,P<0.001）．Cox proportional hazard regression analysis showed that HR in the uncorrected model was 2.31（1.25-4.28）,P<0.001．In the fully corrected model,HR was 2.48（1.37-4.51）and P=0.005,suggesting that malnutrition was associated with a significantly higher risk of all-cause mortality compared with normal nutritional status. Conclusions Low GNRI is an independent risk factor for all-cause death in AECOPD patients．

Key words: elderly nutrition risk index, AECOPD, death