减重手术对炎症因子影响的研究进展

doi:10.3969/j.issn.1000-8535.2024.05.003

摘要/Abstract

摘要： 肥胖是一种以慢性低度炎症为特征的进展性疾病,与多种代谢性疾病的发生、发展密切相关。脂肪组织作为一种内分泌和免疫器官,可分泌多种生物活性物质及炎症因子,参与肥胖患者体内的代谢过程。减重手术是治疗病态性肥胖及相关代谢性疾病的有效方法之一,能够调节机体内的炎症反应、有效改善代谢状态。但减重手术对于炎症因子的作用如何,目前国内外的文献证据仍有争议。本文将系统阐述肥胖与代谢性炎症的关系以及减重手术对炎症因子的影响,旨在为肥胖代谢外科的诊疗过程提供参考。

关键词: 减重手术, 炎症因子, 肥胖, 脂肪组织巨噬细胞

Abstract: Obesity is a progressive disease characterized by chronic low-grade inflammation,which is closely related to the occurrence and development of a variety of metabolic diseases．As an endocrine and immune organ,adipose tissue can secrete a variety of bioactive substances and inflammatory factors,which participate in the metabolic process of obese patients．Bariatric surgery is one of the effective methods for the treatment of morbid obesity and related metabolic diseases,which can regulate the inflammatory response in the machine and effectively improve the metabolic state．However,the effect of bariatric surgery on inflammatory factors is still controversial at home and abroad．This article will systematically explain the relationship between obesity and metabolic inflammation and the effect of bariatric surgery on inflammatory factors,aiming to provide a reference for the diagnosis and treatment process of bariatric surgery．

Key words: bariatric surgery, inflammatory factors, obesity, adipose tissue macrophages

谢娟, 李汝峰, 陈婧, 李珉珉. 减重手术对炎症因子影响的研究进展[J]. 广州医药, 2024, 55(5): 463-471.

XIE Juan, LI Rufeng, CHEN Jing, LI Minmin. Research progress on the impact of bariatric surgery on inflammatory factors[J]. Guangzhou Medical Journal, 2024, 55(5): 463-471.

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