影响不全流产期待治疗效果的相关因素分析

doi:10.3969/j.issn.1000-8535.2023.06.006

广州医药 ›› 2023, Vol. 54 ›› Issue (6): 34-38.DOI: 10.3969/j.issn.1000-8535.2023.06.006

影响不全流产期待治疗效果的相关因素分析

吴彩林, 张丽, 胡端林, 宋健, 曾胜, 王耀楷

香港大学深圳医院妇科（深圳 518048）

收稿日期:2022-09-07 出版日期:2023-06-20 发布日期:2023-07-27
通讯作者: 王耀楷 ,E-mail：paperauthormail@126.com
基金资助:
广东省医学科学技术研究基金（A2020265）

Analysis of factors associated with the effect of expectant treatment of incomplete abortion

WU Cailin, ZHANG Li, HU Duanlin, SONG Jian, ZENG Sheng, WANG Yaokai

Department of Gynecology,the University of Hong Kong-Shenzhen Hospital,Shenzhen 518048,China

Received:2022-09-07 Online:2023-06-20 Published:2023-07-27

摘要/Abstract

摘要： 目的探讨影响宫腔修复的因素,为不全流产妇女选择期待治疗提供理论依据。方法 2021年1月—12月在香港大学深圳医院招募早孕药流不全的患者534例,记录其人口学特征以及从排胎到流产后3周到月经复潮后的相关情况,通过多因素Logistic回归分析影响不全流产者宫腔修复的因素。结果 534例药流不全患者中,月经复潮后宫腔残留240例,残留率为44.9%;多因素Logistic回归分析显示,BMI（OR=0.888,95%CI：0.808~0.975）、子宫位置（OR=1.836,95%CI：1.139~2.958）、人工流产次数（OR=2.258,95%CI：1.078~4.728）、阴道流血时长（OR=0.344,95%CI：0.141~0.837）、残留物最大径线（OR=1.061,95%CI：1.031~1.092）、残留物血流信号2级/3级（OR=3.636,95%CI：1.790~7.394;OR=4.001,95%CI：1.561~10.256）是宫腔残留的影响因素。结论宫腔残留的高危因素有子宫后位、残留物最大径线、1次以上的人工流产、2级及以上的残留物血流信号,且血流信号等级影响最大。BMI和阴道流血时长>3周是宫腔残留的保护因素。

关键词: 不全流产, 宫腔残留, 危险因素, 前瞻研究

Abstract: Objective To investigate the factors affecting uterine cavity repair and to provide a theoretical basis for the choice of expectant treatment for women with incomplete abortion．Methods From January to December 2021,534 patients with incomplete abortions were recruited at University of Hong Kong-Shenzhen Hospital,and their demographic characteristics and correlations from expulsion of the gestational sac to 3 weeks after medication abortion and after menstrual resumption were recorded,and the factors affecting uterine cavity repair in incomplete abortions were analyzed by multifactorial logistic regression．Results In 534 women,there were 240 cases of uterine cavity remnants after menstrual return,with a remnant rate of 44.9%;the results of multifactorial logistic regression analysis showed that BMI（OR=0.888,95% CI：0.808-0.975）,uterine position（OR=1.836,95% CI：1.139-2.958）,number of abortions（OR=2.258,95% CI：1.078-4.728）,length of vaginal bleeding（OR=0.344,95% CI：0.141-0.837）,maximum diameter of residuals（OR=1.061,95% CI：1.031-1.092）,and residual blood flow signal grade 2/3（OR=3.636,95% CI：1.790-7.394;OR=4.001,95%CI：1.561-10.256）were influential factors for uterine residuals．Conclusions High-risk factors for uterine residuals are posterior uterus,the maximum diameter of residuals,more than one abortion,grade 2 or higher residual blood flow signal,and the grade of blood flow signal had the greatest effect．BMI and duration of vaginal bleeding >3 weeks are protective factors for uterine residuals．

Key words: incomplete abortion, uterine residuals, risk factors, prospective study

吴彩林, 张丽, 胡端林, 宋健, 曾胜, 王耀楷. 影响不全流产期待治疗效果的相关因素分析[J]. 广州医药, 2023, 54(6): 34-38.

WU Cailin, ZHANG Li, HU Duanlin, SONG Jian, ZENG Sheng, WANG Yaokai. Analysis of factors associated with the effect of expectant treatment of incomplete abortion[J]. Guangzhou Medical Journal, 2023, 54(6): 34-38.

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影响不全流产期待治疗效果的相关因素分析

Analysis of factors associated with the effect of expectant treatment of incomplete abortion

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