广州医药 ›› 2022, Vol. 53 ›› Issue (1): 87-90.DOI: 10.3969/j.issn.1000-8535.2022.01.018

• 论著 • 上一篇    下一篇

广东省小榄地区急性上消化道出血患者临床特征及其危险因素

赖智权, 周星求, 麦伟流   

  1. 中山市小榄人民医院急诊科(中山 528415)
  • 收稿日期:2021-05-19 出版日期:2022-01-20 发布日期:2022-04-12

Clinical characteristics and risk factors of acute upper gastrointestinal bleeding in Xiaolan District, Guangdong Province

LAI Zhiquan, ZHOU Xingqiu, MAI Weiliu   

  1. Department of Emergency, Xiaolan People's Hospital, Zhongshan 528415, China
  • Received:2021-05-19 Online:2022-01-20 Published:2022-04-12

摘要: 目的 上消化道出血发作急、变化快,具有较高的危险性,本研究目的在于分析急性上消化道出血患者的临床特征及危险因素,为临床诊治提供参考。方法 将2019年1月—2021年2月年我院的242例疑似急性上消化道出血患者作为研究对象,收集患者的年龄、性别、是否有长期抽烟史、饮酒史,是否有合并症以及并发症等一般资料,运用单因素分析其临床特征,运用多因素Logistic回归分析其独立危险因素。结果 患者年龄、长期饮酒史、消化性溃疡、门脉高压、急性胃黏膜病变、服用阿司匹林(ASA药物)、Hp感染等临床特征与急性上消化道出血具有相关性,与患者的性别、长期抽烟史不具有相关性;年龄、消化性溃疡、门脉高压、服用ASA药物、Hp感染是急性上消化道出血的危险性因素。结论 急性上消化道出血病势程度较重,死亡率高,出血需及时针对性治疗;对于急性上消化道出血高危患者,严密监测病情变化,评估其风险系数。

关键词: 急性上消化道出血, 临床特征, 危险因素分析

Abstract: Objective Upper gastrointestinal bleeding has a high risk because of its rapid change. The purpose of this study is to analyze the clinical characteristics and risk factors of patients with acute upper gastrointestinal bleeding, so as to provide reference for clinical diagnosis and treatment. Methods A total of 242 patients with suspected acute upper gastrointestinal bleeding in our hospital from January 2019 to February 2021 were selected as the research objects. The general data such as patients' age, gender, whether they had a long-term history of smoking or drinking, whether they had complications and data of complications were collected. The clinical characteristics were analyzed by univariate analysis, and the independent risk factors were analyzed by multivariate Logistic regression analysis. Results Age, long-term drinking history, peptic ulcer, portal hypertension, acute gastric mucosal lesions, taking aspirin (ASA drugs), Hp infection and other clinical characteristics were correlated with acute upper gastrointestinal bleeding, but gender and long-term smoking history were not. Age, peptic ulcer, portal hypertension, taking ASA drugs and Hp infection were the risk factors of acute upper gastrointestinal bleeding. Conclusion The acute upper gastrointestinal bleeding is a serious disease, with high mortality, and the bleeding needs timely targeted treatment. For patients with high-risk acute upper gastrointestinal bleeding, closely monitor the changes of the disease and evaluate the risk coefficient are needed.

Key words: acute upper gastrointestinal bleeding, clinical features, risk factors analysis