血清IL-33水平与老年COPD患者病程分期的相关性研究

doi:10.3969/j.issn.1000-8535.2016.06.008

广州医药 ›› 2016, Vol. 47 ›› Issue (6): 26-28.DOI: 10.3969/j.issn.1000-8535.2016.06.008

血清IL-33水平与老年COPD患者病程分期的相关性研究

冯聪锐, 何力敏, 徐刚

广州市第一人民医院老年病科(广州 510180)

收稿日期:2016-08-29 出版日期:2016-11-20 发布日期:2021-12-02
基金资助:
广州市卫生医药科技项目(20161A010002)

Relevant research between serum IL-33 level and the stage of disease in elderly patients with chronic obstructive pulmonary disease

Feng Congrui, He Limin, Xu Gang

Department of Geriatrics, Guangzhou First People's Hospital, Guangzhou 510180, China

Received:2016-08-29 Online:2016-11-20 Published:2021-12-02

摘要/Abstract

摘要： 目的研究老年慢性阻塞性肺病(COPD)患者血清IL-33水平与其病程分期的相关性。方法选择60例老年COPD患者作为观察组,按病程分期分为稳定期组和急性加重组,另选择15例非COPD老年患者作为对照组;分别检测血清IL-33水平。结果各组组间比较结果显示,AECOPD组和COPD稳定期组的血清IL-33水平均高于对照组(P<0.05),其中,AECOPD组的比COPD稳定期组的更高(P<0.05)。结论血清IL-33水平在老年COPD患者中增高,急性加重期更明显,提示IL-33在老年人COPD发生、发展中可能起重要作用。

关键词: 老年人, 慢性阻塞性肺病, IL-33, 发病机制

Abstract: Objective To have relevant research between serum IL-33 level and the stage of disease in elderly patients with chronic obstructive pulmonary disease(COPD). Methods 60 elderly patients with COPD were selected as the observation group, who were divided into stable COPD group and AECOPD group. The other 15 patients with non-COPD were selected as the control group. The serum IL-33 levels were detected respectively. Results The comparison results between the groups showed that the serum IL-33 levels in the AECOPD group and the stable COPD group were higher than those in the control group(P<0.05), which was higher in the AECOPD group than in the COPD group(P<0.05). Conclusion Serum IL-33 levels were increased in elderly patients with COPD, the increase in acute exacerbation was more obvious, suggesting that IL-33 may play an important role in the occurrence and development of COPD in the elderly.

Key words: Elderly, Chronic obstructive pulmonary disease, IL-33, Pathogenesis

冯聪锐, 何力敏, 徐刚. 血清IL-33水平与老年COPD患者病程分期的相关性研究[J]. 广州医药, 2016, 47(6): 26-28.

Feng Congrui, He Limin, Xu Gang. Relevant research between serum IL-33 level and the stage of disease in elderly patients with chronic obstructive pulmonary disease[J]. Guangzhou Medical Journal, 2016, 47(6): 26-28.

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血清IL-33水平与老年COPD患者病程分期的相关性研究

Relevant research between serum IL-33 level and the stage of disease in elderly patients with chronic obstructive pulmonary disease

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