围术期凝血功能障碍和TEG检测

doi:10.3969/j.issn.1000-8535.2015.02.039

广州医药 ›› 2015, Vol. 46 ›› Issue (2): 97-100.DOI: 10.3969/j.issn.1000-8535.2015.02.039

围术期凝血功能障碍和TEG检测

李晋, 衡新华

昆明医科大学第一附属医院麻醉科(昆明 650032)

收稿日期:2014-12-04 发布日期:2021-11-30
通讯作者: 衡新华,Email-hengxinhua06@sina.cn

Perioperative blood coagulation dysfunction and TEG(Thromboelastography)

LI Jin, Heng Xinhua

Anesthesia department of the First Affiliated Hospital of Kunming Medical University,Kunming 650032,China

Received:2014-12-04 Published:2021-11-30

摘要/Abstract

摘要： 凝血功能障碍是围术期临床关注的重点,评价方式较多,其中血栓弹力图(TEG)可根据凝血过程中血凝块的黏弹性变化所描绘出的图像,反映全血的凝血和纤溶能力,其结果快速准确,被广泛应用围术期凝血功能监测。

关键词: 围术期凝血功能障碍, 血栓弹力图, 输血, 高凝状态, 血栓防治

Abstract: Coagulopathy is a key concern around operation period.Thromboelastography (TEG) is in the process of image based on viscoelastic changes of coagulation of blood clots depicted, to reflect the blood coagulation and fibrinolytic capacity. TEG test result is quickly and accurately, therefore it is widely used in the perioperative monitoring of blood coagulation function, blood transfusion guide, hypercoagulation monitoring, prevention of thrombosis.

Key words: Perioperative blood coagulation, Thromboelastography, Blood transfusion, Hypercoagulation, Prevention of thrombosis

李晋, 衡新华. 围术期凝血功能障碍和TEG检测[J]. 广州医药, 2015, 46(2): 97-100.

LI Jin, Heng Xinhua. Perioperative blood coagulation dysfunction and TEG(Thromboelastography)[J]. Guangzhou Medical Journal, 2015, 46(2): 97-100.

参考文献

[1] Macafee B,Campbell JP,Ashpole K, et al. Reference ranges for thromboelastography (TEG) and traditional coagulation tests in term parturients undergoing caesarean section under spinal anaesthesia[J]. Anaesthesia, 2012,67(7):741-747.
[2] Cosmi B,Alatri A,Cattaneo M,et al. Assessment of the risk of bleeding in patients undergoing surgery or invasive procedures:guidelines of the Italian society for haemostasis and thrombosis (SISET)[J].Thromb Res, 2009,124(5):e6-e12.
[3] Dunham CM,Rabel C,Hileman BM, et al. TEG^®and Rapid TEG^® are unreliable for detecting warfarin-coagulopathy: a prospective cohort study[J]. Thromb,2014,12(1):4.
[4] Agren A,Wikman AT,Ostlund A, et al.TEG(R) functional fibrinogen analysis may overestimate fibrinogen levels[J]. Anesth Analg,2014,118(5):933-935.
[5] Nystrup KB, Windelov NA, Thomsen AB, et al. Reduced clot strength upon admission, evaluated by thrombelastography (TEG), in trauma patients is independently associated with increased 30-day mortality[J]. Scand J Trauma Resusc Emerg Med,2011(19):52.
[6] Robeys LN,Patel RK,Arya R.Haemostasis and thrombosis in liver disease[J].Br J Haematol, 2010,148(4):507-521.
[7] Venema LF, Post WJ,Hendriks HG,et al. An Assessment of Clinical Interchangeability of TEG^® and RoTEM^® Thromboelastographic Variables in Cardiac Surgical Patients[J]. Anesth Analg,2010,111(2):339-344.
[8] Welsh KJ,Padilla A,Dasgupta A,et al. Thromboelastography Is a Suboptimal Test for Determination of the Underlying Cause of Bleeding Associated With Cardiopulmonary Bypass and May Not Predict a Hypercoagulable State[J]. Am J Clin Pathol, 2014,142(4):492-497.
[9] Bolliger D, Seeberger MD, Tanaka KA. Principles and Practice of Thromboelastography in Clinical Coagulation Management and Transfusion Practice[J]. Transfus Med Rev J,2012,26(1): 1-13.
[10] Sun W, Jeleniowski K, Zhao X, et al. Thromboelastography (TEG)-based algorithm reduces blood product utilization in patients undergoing VAD implant[J]. J Card Surg,2014,29(2):238-243.
[11] Tapia NM, Chang A, Norman M, et al. TEG-guided resuscitation is superior to standardized MTP resuscitation in massively transfused penetrating trauma patients[J]. J Trauma Acute Care Surg,2013,74(2):378-386.
[12] Bisehof D,Dalbert S,Zollinger A,et al. Thrombelastography in the surgical patient[J].Minerva Anestcsiol,2010,76(2):131-137.
[13] Turker G,Yilmazlar T,Mogol EB,et al. The Effects of Colloid Pre-Loading on Thromboelastography Prior to Caesarean Delivery: Hydroxyethyl Starch 130/0.4 versus Succinylated Gelatine[J]. Journal of International Medical Research, 2011,39(1):143-149.
[14] Agren A, Wikman AT, Holmstrom M, et al. Thromboelastography (TEG(R)) compared to conventional coagulation tests in surgical patients-a laboratory evaluation[J]. Scand J Clin Lab Invest,2013,73(3):214-220.
[15] Karon BS.Why is everyone so excited about thromboelastrography(TEG)? [J]. Clin Chim Acta,2014,(436):143-148.
[16] Roche AM,James MF,Grocott MP,et al.Just scratching the surface: varied coagulation effects of polymer containers on TEG variables[J]. Eur J Anaesthesiol,2006,23(1):45-49.
[17] Okamura K,Nakagawa I,Hidaka S,et al. Perioperative changes of blood coagulability evaluated by thromboelastography (TEG) in patients undergoing total knee and total hip arthroplasty[J]. Masui,2007,56(6):645-649.
[18] Kashuk JL,Moore EE,Sabel A,et al. Rapid thrombelastography (r-TEG) identifies hypercoagulability and predicts thromboembolic events in surgical patients[J]. Surgery,2009,146(4):764-772.
[19] Pivalizza EG. TEG and perioperative hypercoagulability[J]. Anesth Analg,2006,102(1):334-335.
[20] Gurbel PA,Bliden KP,Guyer K,et al.Delayed thrombin-induced platelet-fibrin clot generation by clopidogrel:A new dose-related effect demonstrated by thrombelastography in patients undergoing coronary artery stenting[J]. J Thromb Res,2007,119(5):563-570.
[21] Afshari A, Wikkelso A, Brok J, et al. Thrombelastography (TEG) or thromboelastometry (ROTEM) to monitor haemotherapy versus usual care in patients with massive transfusion[J]. Cochrane Database Syst Rev,2011(3):CD007871.

围术期凝血功能障碍和TEG检测

Perioperative blood coagulation dysfunction and TEG(Thromboelastography)

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 3

编辑推荐

Metrics

本文评价

[1]	李伟娜. 阿司匹林联合低分子肝素治疗高凝状态复发性流产的效果观察[J]. 广州医药, 2021, 52(2): 131-134.
[2]	陈红霞. ELISA联合NAT技术在献血者血液筛查和输血残余风险分析中的应用[J]. 广州医药, 2020, 51(6): 117-119.
[3]	庄运芳, 黄璐, 叶登凰, 刘丽华, 黄仕云, 聂湘辉. 河源地区医疗机构临床用血合理性调查分析[J]. 广州医药, 2018, 49(4): 82-84.