广州医药 ›› 2019, Vol. 50 ›› Issue (3): 23-26.DOI: 10.3969/j.issn.1000-8535.2019.03.006

• 论著 • 上一篇    下一篇

儿童危重症乙型流行性感冒7例临床分析

房春晓, 杨峰霞, 谭丽梅, 王艳玲, 徐翼, 叶家卫   

  1. 广州市妇女儿童医疗中心感染科(广州 510120)
  • 收稿日期:2019-01-23 出版日期:2019-05-20 发布日期:2021-12-17
  • 通讯作者: 叶家卫,E-mail: 888yie@sina.com

Clinical analysis of 7 children with severe influenza B

FANG Chunxiao, YANG Fengxia, TAN Limei, WANG Yanling, XU Yi, YE Jiawei   

  1. Department of Infectious Disease,Guangzhou Women and Children's Medical Center,Guangzhou 510120,China
  • Received:2019-01-23 Online:2019-05-20 Published:2021-12-17

摘要: 目的 分析儿童危重症乙型流感患者的临床特点,提高临床医师对此危重症的认识水平。方法 对2017年12月—2018年2月广州市妇女儿童医疗中心收治的7例儿童危重症乙型流感患者的临床资料进行回顾性分析。结果 危重患儿好发年龄以幼儿及学龄前期为主。5例表现为呼吸衰竭,1例表现为心源性休克,1例表现为急性坏死性脑病。起病初(3 d内)均未见白细胞减少,白细胞数最高28.1×109/L。白细胞分类以中性粒细胞为主。痰培养出流感嗜血杆菌、肺炎链球菌各1例。3例存在塑型性支气管炎改变。经积极治疗,体温恢复正常最短2 d,最长7 d,平均(4.20±1.79) d。住院时间最短12 d,最长23 d,平均(16.71±3.90)d。结论 乙型流感危重患儿临床表现多样,可累及多个系统器官;呼吸道合并症最多见,可出现塑型性支气管炎改变;及早识别及积极治疗,预后良好。

关键词: 儿童, 危重症, 乙型流行性感冒, 回顾性分析

Abstract: Objective To analyze the clinical characteristics of the children with severe influenza B and to provide reference for identifying severe cases. Methods Clinical data of 7 children with severe influenza B were retrospectively analyzed. Results The age ranged from 11 months to 7 years old, with an average was (4.13±2.06) years old. Five cases were characterized by respiratory failure, one by cardiogenic shock and one by acute necrotizing encephalopathy. No leukopenia was observed at the beginning of the disease(in 3 days), and the number of white blood cells was as high as 28.1×109/L, White blood cell classification is dominated by neutrophils. haemophilus influenzae and streptococcus pneumoniae were produced by sputum culture in 1 case for each. Three patients had plastic bronchitis changes. After active treatment, the body temperature returned to normal with minimum 2 days, longest 7 days and average (4.20+1.79)days. The length of stay was the shortest 12 days, the longest 23 days, and the average (16.71+3.90) days. Conclusion The clinical manifestations of severe influenza B are diverse and may involve multiple system organs. Respiratory complications were the most common, with plastic bronchitis changes. Early recognition and active treatment had a good prognosis.

Key words: Children, Influenza B, Clinical characteristics, Retrospective studies