广州医药 ›› 2016, Vol. 47 ›› Issue (3): 61-63.DOI: 10.3969/j.issn.1000-8535.2016.03.022

• 论著 • 上一篇    下一篇

规范二级预防下老老年人轻型卒中复发危险因素分析

吴小燕1, 陈婷2, 秦琴保3   

  1. 1 广州市增城区人民医院神经内科(广州 511300)
    2 广州医科大学公共卫生学院 (广州 510180)
    3 广州市第一人民医院老年神经科(广州 510180)
  • 收稿日期:2016-02-04 出版日期:2016-05-20 发布日期:2021-11-30
  • 通讯作者: 秦琴保,E-mail:qbqin@tom.com

Analysis of risk factors for recurrence of minor ischemic stroke in aged patients who received standardized secondary prevention

Wu Xiaoyan, Chen Ting, Qin Qinbao   

  1. Wu Xiaoyan, Department of Neurology, Zengcheng People's Hospital, Guangzhou 511300, China
    Chen Ting,Public Health College, Guangzhou Medical University, Guangzhou 510180, China
    Qin Qinbao, Department of Geriatrics Neurology, Guangzhou First People's Hospital, Guangzhou 510180, China
  • Received:2016-02-04 Online:2016-05-20 Published:2021-11-30

摘要: 目的 探讨规范二级预防下老老年人轻型卒中复发的危险因素。方法 收集我院80岁及以上、既往有轻型卒中病史、并进行规范二级预防半年以上的老老年患者的临床资料:一般资料、既往病史及用药情况、入院时血压及基础生化指标、影像学资料、缺血性卒中复发情况。根据有无复发缺血性卒中将患者分为复发组和无复发组两组,分析以上因素在两组间的差异。结果 80例患者中复发缺血性脑卒中共26例,复发率32.5%。统计结果显示,轻型卒中复发组与合并高血压病、入院时收缩压、D二聚体水平呈正相关,其相关系数分别为0.265(P=0.018)、0.232(P=0.038)和0.222(P=0.048)。复发组收缩压升高比例高于无复发组(χ2=6.919,P=0.031)。非条件Logistic多因素分析显示:合并高血压病[OR 95%CI=(1.162,10.230)]、收缩压升高[OR 95%CI=(0.997,68.840)]与轻型缺血性卒中复发相关。结论 合并高血压病、收缩压升高是老老年人轻型卒中规范二级预防下复发独立危险因素。

关键词: 老老年, 规范二级预防, 轻型卒中, 复发

Abstract: Objective To analyze the recurrence risk factors of aged patients with minor ischemic stroke under standardized secondary prevention. Methods Patients over 80 years old and with minor ischemic stroke history were enrolled, and the following data were collected: demographic characteristics, medical history, current medicine, blood test, imaging findings and recurrence of ischemic strokes. Patients were divided into two groups: the recurrence group and the non-recurrence group. Chi-square test,logistic regression models were performed to assess correlations between baseline variables and recurrence of minor stroke events. Results In our study, 26 patients had recurrent minor ischemic stroke(32.5%). The prevalence of recurrence of minor stroke was positively correlated with hypertension(CI 0.265, P 0.018), SBP(CI 0.232,P 0.038), d-2-dimer(CI 0.232,P 0.048). Patients in recurrence group are more likely to presented with SBP elevation compared to non-recurrence group(χ2=6.919, P=0.031). Unconditional logistic regression analysis showed that hypertension, especially high SBP significantly related to minor ischemic stroke recurrence. Conclusion Hypertension,especially elevated SBP, were considered as an independent risk factors for aged old patients with minor ischemic stroke who received standardized secondary prevention.

Key words: Aged old, Standardized secondary prevention, Minor ischemic stroke, Recurrence