广州医药 ›› 2020, Vol. 51 ›› Issue (1): 14-18.DOI: 10.3969/j.issn.1000-8535.2020.01.004

• 论著 • 上一篇    下一篇

实时超声弹性成像技术评估脑卒中患者颈动脉斑块稳定性的应用研究

张秀玲   

  1. 广州市第一人民医院,华南理工大学附属第二医院超声医学科(广州 510180)
  • 收稿日期:2019-08-09 出版日期:2020-01-20 发布日期:2021-11-28
  • 基金资助:
    广州市卫生健康科技项目(20191A010017);广州市中医药和中西医结合科技项目(20192A010003)

Application of real-time ultrasound elastography in assessing the stability of carotid atherosclerotic plaque in stroke patients

ZHANG Xiuling   

  1. Department of Medical Ultrasound, Guangzhou First People's Hospital,The Second Affiliated Hospital of South China University of Technology, Guangzhou 510180,China
  • Received:2019-08-09 Online:2020-01-20 Published:2021-11-28

摘要: 目的 探讨实时超声弹性成像技术联合常规超声检查在评估脑卒中患者颈动脉粥样硬化斑块稳定性中的临床应用价值。方法 收集我院收治的临床确诊脑卒中患者(卒中组)34例作为研究对象,另抽取同期存在颈动脉斑块但未发生过脑卒中的人群(对照组)56例作为对照研究对象,进行超声弹性成像检测,并对检查结果进行统计分析。结果 34例脑卒中患者发现颈动脉粥样硬化斑块57个,其中低回声斑块29个,混合回声斑块21个,强回声斑块7个;56例对照组患者发现颈动脉粥样硬化斑块75个,其中低回声斑块22个,混合回声斑块25个,强回声斑块28个;两组间比较斑块数量之间、斑块大小之间差异有统计学意义(P<0.05)。颈动脉粥样硬化低回声、混合回声及强回声斑块弹性评分依次升高,其斑块硬度值依次升高;两组间斑块的评分数量分布差异有统计学意义(P<0.05);对于同一类型斑块的硬度值两组间差异无统计学意义(P>0.05);脑卒中组不同类型斑块间的硬度值差异有统计学意义(P<0.05)。结论 超声弹性成像技术可对脑卒中患者颈动脉粥样硬化斑块的稳定性进行半定量评估,不同类型斑块因所含组织成分的不同其弹性应变率表现也不同,能有效补充常规超声检查的信息的不足,进而评估斑块的稳定性。

关键词: 超声弹性成像技术, 脑卒中, 颈动脉粥样硬化, 弹性评分, 弹性应变率

Abstract: Objective To explore the clinical value of real-time ultrasound elastography combined with conventional ultrasound in assessing the stability of carotid atherosclerotic plaques in stroke patients. Methods Thirty-four patients with clinically confirmed stroke (stroke group) in our hospital were collected as the research object. Another 56 patients with carotid plaque but without stroke (control group) in the same period were selected as the control object for ultrasonic elastography detection, and the results were analyzed statistically. Results Thirty-four stroke patients were found 57 carotid atherosclerotic plaques, including 29 hypoechoic plaques, 21 mixed echoic plaques and 7 hyperechoic plaques; 56 control patients were found 75 carotid atherosclerotic plaques, including 22 hypoechoic plaques, 25 mixed echoic plaques and 28 hyperechoic plaques. There were significant differences between the number of plaques and the size of plaques (P<0.05). Carotid atherosclerosis low echo, mixed echo and strong echo plaque elasticity score increased in turn, the plaque hardness value increased in turn; the number of plaque scores between the two groups had statistical significance (P<0.05); for the same type of plaque hardness value between the two groups had no significant difference (P>0.05); There were significant differences in hardness values between the same types of plaques (P<0.05). Conclusion Ultrasound elastography may semi-quantitatively evaluate the stability of carotid atherosclerotic plaques in stroke patients. Different types of plaques have different elastic strain rates because of different tissue components. It may effectively complement the information deficiency of conventional ultrasound examination, and then evaluate the stability of plaques.

Key words: Ultrasound elastography, Stroke, Carotid atherosclerosis, Elastic score, Elastic strain rate