关键词: 四子散, 股骨骨折, 术后疼痛, 中药封包, 药熨

Abstract: Objective To explore the clinical efficacy and safety of Sizi powder pack hot compress in the treatment of pain and swelling after femoral fracture surgery．Methods From June 2024 to May 2025,60 patients after femoral fracture surgery were admitted to the Orthopedics Department of Wuyuan County People's Hospital and randomly divided into observation group（30 cases,conventional treatment+Sizi power pack hot compress）and control group（30 cases,conventional treatment）． The pain score（NRS-11）,swelling score,CRP,IL-6 levels and incidence of adverse events before and after treatment were compared between the two groups．Results There was no significant difference in pain and swelling scores between the two groups before treatment（P>0.05）．After 1 week of treatment,the pain score（2.11±0.48）,swelling score（0.35±0.43）,CRP（12.23±3.12 mg/L）,IL-6（16.03±4.01 ng/L）levels in the observation group were significantly lower than those in the control group（3.54±0.56,1.04±0.58,24.31±4.51 mg/L,16.03+4.01 ng/L）,and the difference was statistically significant（P<0.001）．There were no adverse events in the observation group or the control group．Conclusions Sizi power pack hot compress can significantly alleviate the pain and swelling after femoral fracture surgery,and with good safety．

Key words: Sizi powder, femoral fracture, postoperation pain, powder packet, hot compress