广州医药 ›› 2025, Vol. 56 ›› Issue (4): 500-504.DOI: 10.20223/j.cnki.1000-8535.2025.04.009

• 论著 • 上一篇    下一篇

宫腔镜病灶切除术与超声监测下吸宫术治疗剖宫产瘢痕部位妊娠的有效性比较

李秋兰, 梁双燕, 曹智英, 陈柠, 黄庭婷, 罗秋燕   

  1. 南宁市妇幼保健院妇女保健科(广西南宁 530011)
  • 收稿日期:2024-04-11 出版日期:2025-04-20 发布日期:2025-05-07
  • 基金资助:
    广西壮族自治区卫生健康委员会自筹经费科研课题(Z20211270)

Comparison of effectiveness between hysteroscopic resection surgery and ultrasound-guided uterine aspiration in the treatment of cesarean scar pregnancy

LI Qiulan, LIANG Shuangyan, CAO Zhiying, CHEN Ning, HUANG Tingting, LUO Qiuyan   

  1. Women’s Health Department,Nanning Maternal and Child Health Hospital,Nanning 530011,China
  • Received:2024-04-11 Online:2025-04-20 Published:2025-05-07

摘要: 目的 比较宫腔镜病灶切除术与超声监测下吸宫术治疗剖宫产瘢痕部位妊娠(CSP)的有效性。方法 回顾性分析2021年7月—2023年10月在南宁市妇幼保健院确诊为I、Ⅱ型CSP并接受治疗的129例患者,停经时间在38~83 d,中位停经时间48 d。其中42例患者接受了宫腔镜病灶切除术治疗(A组),87例患者接受超声监测下吸宫术治疗(B组),比较两组患者术后1、3、7、14 d的人绒毛膜促性腺激素水平以及手术出血量、手术时间、住院时间、住院花费。结果 两组患者在术后1 d,血清HCG水平下降,下降幅度均超过50%,且A组患者术后1 d血清HCG的下降幅度及下降速率大于B组患者(P<0.05);术后3、7、14 d,两组血清HCG水平仍持续下降。另外,A组患者手术出血量、手术时间、住院时间、住院花费分别为(15.35±14.53)mL、(60.73±53.05)min、(4.33±1.90)d、(6 689.23±2 216.19)元;B组患者手术出血量、手术时间、住院时间、住院费用分别为(26.09±29.24)mL、(51.59±54.46)min、(4.82±1.83)d、(6 270.34±2 547.85)元。A组患者术中出血量低于B组、住院时间短于B组(P<0.05),手术时间及住院费用与B组比较差异无统计学意义(P均>0.05)。结论 宫腔镜病灶切除术与超声监测下吸宫术均能有效治疗CSP,但宫腔镜病灶切除术在术后血清HCG的下降幅度及下降速率、术中出血量、住院时间等方面优于超声监测下吸宫术,而且手术时间和住院费用并没有显著增加。

关键词: 剖宫产瘢痕部位妊娠, 宫腔镜病灶切除术, 超声监测下吸宫术

Abstract: Objective To compare the efficacy between hysteroscopic resection surgery and ultrasound-guided uterine aspiration in the treatment of cesarean scar pregnancy(CSP).Methods A retrospective analysis was performed in 129 patients diagnosed with CSP(type I or Ⅱ)and treated in Nanning Maternal and Child Health Hospital from July 2021 to October 2023.Their duration of amenorrhea was between 38~83 d,with a median of 48 days.Among them,42 patients were treated with hysteroscopic resection surgery therapy(group A),87 patients were treated with ultrasound-guided uterine aspiration therapy and(group B).Then,the levels of human chorionic gonadotropin(HCG),the amount of the intraoperative bleeding volume,surgical time,hospitalization time,and hospitalization expenses were compared between the two groups at one,three,seven and 14 days postoperativey.Results After one day of surgery,the serum HCG levels of two groups significantly decreased,with a decrease of more than 50%,and the magnitude and rate of decrease in serum HCG levels of group A were significantly larger than those of group B(P<0.05);After three,seven,and 14 day of surgery,serum HCG levels continued to decrease.Furthermore,the intraoperative bleeding volume,surgical time,hospitalization time,hospitalization expenses in group A were(15.35±14.53)mL,(60.73±53.05)min,(4.33±1.90)d,(6 689.23±2 216.19)yuan,respectively.That in group B were(26.09±29.24)mL,(51.59±54.46)min,(4.82±1.83)d,(6 270.34±2 547.85)yuan,respectively.Compared to group B,the intraoperative bleeding volume of group A was significantly lower(P<0.05),and the hospitalization time is shorter,while there was no significant difference in surgical time and hospitalization expenses.Conclusions Both of hysteroscopic resection surgery and ultrasound-guided uterine aspiration can treat cesarean scar pregnancy effectively,but the former is superior to the latter in terms of the magnitude and rate of decrease in serum HCG levels after surgery,intraoperative bleeding volume,and hospitalization time,with no significant increase in surgical time and hospitalization expenses.

Key words: cesarean scar pregnancy, hysteroscopic resection surgery, ultrasound-guided uterine aspiration