广州医药 ›› 2023, Vol. 54 ›› Issue (1): 30-33.DOI: 10.3969/j.issn.1000-8535.2023.01.005

• 论著 • 上一篇    下一篇

不同年龄段皮罗序列征患儿动脉血气分析的特点、机械通气及住院时间比较

张云燕1, 崔颖秋1, 李有强2   

  1. 1 广州市妇女儿童医疗中心口腔科(广州 510120)
    2 南方医科大学附属何贤纪念医院检验科(广州 511400)
  • 收稿日期:2021-09-23 出版日期:2023-01-20 发布日期:2023-02-07
  • 通讯作者: 李有强,E-mail:liyouqiang21@126.com
  • 基金资助:
    广东省卫生健康适宜技术推广项目(166)

Characteristics of arterial blood gas analysis, time of mechanical ventilation and hospital stay in children with Pirre Robin sequence at different ages

ZHANG Yunyan1, CUI Yingqiu1, LI Youqiang2   

  1. 1 Department of Stomatology, Guangzhou Women and Children's Medical Center, Guangzhou 510120, China
    2 Department of Laboratory Medicine, He Xian Memorial Hospital, Southern Medical University, Guangzhou 511400, China
  • Received:2021-09-23 Online:2023-01-20 Published:2023-02-07

摘要: 目的 探讨不同年龄段皮罗序列征患儿血气分析的特点、手术后机械通气时间和住院时间。方法 收集新生儿及非新生儿III度皮罗序列征(PRS)患儿各30例,PRS患儿入院后通过桡动脉进行采集血标本进行血气分析,比较2组血标本的 pH 值、PCO2 、PO2 、HCO-3、BE、乳酸、AG、A-aDO2的特点、手术后机械通气时间及住院时间。结果 新生儿组PCO2、HCO-3、BE、乳酸及A-aDO2高于非新生儿组,非新生儿组PO2及AG高于新生儿组。2组pH值、PO2、AG均在正常范围,机械通气及住院时间与乳酸呈正相关,与年龄呈负相关。结论 不同的年龄阶段,PRS患儿的动脉血气分析的结果不同,高乳酸与低年龄PRS患儿手术后机械通气时间及住院时间长。

关键词: 血气分析, 皮罗序列征, 年龄, 乳酸

Abstract: Objective To investigate the characteristics of arterial blood gas analysis, time of mechanical ventilation and hospital stay in different age patients with Pirre Robin sequence (PRS). Methods Sixty children with III-grade PRS were divided into two groups according to their age, as neonate group and non-neonate group. The blood samples were collected from radial artery after admission for blood gas analysis, the characteristics of pH value, partial pressure of carbon dioxide (PCO2), partial pressure of blood oxygen (PO2), bicarbonate ion (HCO-3), base excess (BE), lactic acid (Lac), anion gap (AG) , alveolar artery oxygen pressure difference (A-aDO2) , postoperative mechanical ventilation time and hospital stay were compared between the two groups. Results The levels of PCO2, HCO-3, BE, Lac and A-aDO2 in neonate group were higher than those in non-neonate group, and the levels of PO2 and AG in non-neonate group were higher than those in neonate group. The pH value, PO2 and AG of the two groups were in the normal range. Post-operative mechanical ventilation time and hospital stay were positively correlated with Lac and negatively correlated with age. Conclusions In different age groups, the results of arterial blood gas analysis in PRS children were different, and the time of mechanical ventilation and hospital stay were longer in higher Lac level and younger patients with PRS.

Key words: blood gas analysis, Pirre Robin sequence, age, lactic acid