瑞格列奈联合胰岛素治疗2型糖尿病临床疗效及对患者血糖水平的影响

doi:10.3969/j.issn.1000-8535.2021.04.014

广州医药 ›› 2021, Vol. 52 ›› Issue (4): 65-67.DOI: 10.3969/j.issn.1000-8535.2021.04.014

瑞格列奈联合胰岛素治疗2型糖尿病临床疗效及对患者血糖水平的影响

骆超锋, 梁叠锋, 关国宏

广州市番禺区第六人民医院(广州 511442)

出版日期:2021-07-20 发布日期:2021-11-23

Clinical efficacy of repaglinide combined with insulin in the treatment of type 2 diabetes mellitus and its effect on blood glucose level

LUO Chaofeng, LIANG Diefeng, GUAN Guohong

The Sixth People's Hospital of Panyu District, Guangzhou 511442,China

Online:2021-07-20 Published:2021-11-23

摘要/Abstract

摘要： 目的探讨瑞格列奈联合胰岛素治疗2型糖尿病临床疗效及对患者血糖水平的影响效果。方法选取我院2019年1月—2021年1月收治的2型糖尿病患者324例,用随机数字法分为两组,每组各52例,对照组应用胰岛素治疗,研究组应用瑞格列奈联合胰岛素治疗。对两组2型糖尿病患者的临床疗效、血糖水平(FPG指数、2 h PG指数、HbA1c指数)以及胰岛素水平(HOMA-β水平、HOMA-IR水平)进行比较。结果研究组疗效高于对照组(P＜0.05);研究组治疗后血糖指数优于对照组(P＜0.05);研究组治疗后胰岛素水平优于对照组(P＜0.05)。结论 2型糖尿病患者在治疗时,应用瑞格列奈联合胰岛素治疗,可增强治疗疗效,有效控制血糖水平,改善胰岛功能,从而促进疾病转归,具有极大的推广价值。

关键词: 瑞格列奈, 胰岛素, 2型糖尿病, 临床疗效, 血糖水平

Abstract: Objective To investigate the clinical efficacy of repaglinide combined with insulin in the treatment of type 2 diabetes mellitus and its effect blood glucose level. Methods A total of 324 patients with type 2 diabetes admitted to our hospital from January 2019 to January 2021 were randomly divided into two groups with 52 patients in each group. The control group was treated with insulin, and the research group was treated with repaglinide combined with insulin. Clinical efficacy, blood glucose level (FPG index, 2HPG index, HbA1c index) and insulin level (HOMA-β level, HOMA-IR level) of patients with type 2 diabetes were compared between two groups. Results The therapeutic effect of the research group was higher than that of the control group (P<0.05). The glycemic index of the research group was better than that of the control group (P<0.05). The insulin level in the research group was better than that in the control group (P<0.05). Conclusion In the treatment of type 2 diabetes mellitus, the application of repaglinide combined with insulin can enhance the therapeutic effect, effectively control the blood glucose level, improve the islet function, so as to promote the outcome of the disease, which has great promotion value.

Key words: Repaglinide, Insulin, Type 2 diabetes, Clinical effect, Blood glucose levels

骆超锋, 梁叠锋, 关国宏. 瑞格列奈联合胰岛素治疗2型糖尿病临床疗效及对患者血糖水平的影响[J]. 广州医药, 2021, 52(4): 65-67.

LUO Chaofeng, LIANG Diefeng, GUAN Guohong. Clinical efficacy of repaglinide combined with insulin in the treatment of type 2 diabetes mellitus and its effect on blood glucose level[J]. Guangzhou Medical Journal, 2021, 52(4): 65-67.

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瑞格列奈联合胰岛素治疗2型糖尿病临床疗效及对患者血糖水平的影响

Clinical efficacy of repaglinide combined with insulin in the treatment of type 2 diabetes mellitus and its effect on blood glucose level

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