丹红联合曲克芦丁脑蛋白水解物治疗急性脑梗死疗效分析

doi:10.3969/j.issn.1000-8535.2021.03.006

广州医药 ›› 2021, Vol. 52 ›› Issue (3): 32-35.DOI: 10.3969/j.issn.1000-8535.2021.03.006

丹红联合曲克芦丁脑蛋白水解物治疗急性脑梗死疗效分析

董文韬, 区健刚, 刘彩月, 吕秀武

罗定市人民医院神经内科(罗定 527200)

收稿日期:2020-11-02 发布日期:2021-11-24
基金资助:
云浮市医药卫生项目(2019B047)

Therapeutic effect of Danhong combined with troxerutin cerebroprotein hydrolysate in the treatment of acute cerebral infarction

DONG Wentao, OU Jiangang, LIU Caiyue, LV Xiuwu

Department of Neurology,Luoding People's Hospital, Luoding 527200, China

Received:2020-11-02 Published:2021-11-24

摘要/Abstract

摘要： 目的探讨急性脑梗死采用丹红联合曲克芦丁脑蛋白水解物治疗的效果。方法本文将2019年7月—2020年9月我院收治的88例急性脑梗死患者作为研究对象,应用简单数字表达法将患者随机分为两组,44例对照组和44例实验组,对照组患者应用丹红注射液治疗,实验组患者则在对照组基础上联合曲克芦丁脑蛋白水解物进行治疗,1个疗程后,统计分析用药后有效率、治疗前后NIHSS评分、血液流变学指标。结果两组之间治疗后NIHSS评分、血液流变学指标相比,实验组较对照组低;用药后有效率相比,实验组较对照组高,P＜0.05。结论采用丹红注射液治疗急性脑梗死的基础上给予曲克芦丁脑蛋白水解物治疗可提升疗效,改善患者神经功能缺损状态与血液循环,改善患者预后,促进患者早日康复。

关键词: 急性脑梗死, 丹红注射液, 曲克芦丁脑蛋白水解物, 神经功能缺损

Abstract: Objective To investigate the effect of Danhong combined with troxerutin brain protein hydrolysate in the treatment of acute cerebral infarction. Methods 88 patients with acute cerebral infarction in our hospital from July 2019 to September 2020 were randomly divided into two groups, 44 cases in the control group and 44 cases in the experimental group. The effective rate, NIHSS score and hemorheology indexes before and after treatment were statistically analyzed after one course of treatment. Results After treatment, NIHSS score and hemorheology indexes of the experimental group were lower than those of the control group; the effective rate of the experimental group was higher than that of the control group, P<0.05. Conclusion On the basis of Danhong injection in the treatment of acute cerebral infarction, troxerutin cerebroprotein hydrolysate can improve the curative effect, improve the neurological deficit and blood circulation, improve the prognosis of patients, and promote the early recovery of patients.

Key words: Acute cerebral infarction, Danhong injection, Troxerutin cerebroprotein hydrolysate, Nerve function defect

董文韬, 区健刚, 刘彩月, 吕秀武. 丹红联合曲克芦丁脑蛋白水解物治疗急性脑梗死疗效分析[J]. 广州医药, 2021, 52(3): 32-35.

DONG Wentao, OU Jiangang, LIU Caiyue, LV Xiuwu. Therapeutic effect of Danhong combined with troxerutin cerebroprotein hydrolysate in the treatment of acute cerebral infarction[J]. Guangzhou Medical Journal, 2021, 52(3): 32-35.

参考文献

[1] 李菊琴,代青湘,韩吉祥, 等. 丹红注射液联合曲克芦丁治疗急性脑梗死的疗效及对hs-CRP、TNF-α和IL-6影响[J]. 中华中医药学刊,2019,37(8):2013-2016.
[2] 刘宇恒.长春西汀联合曲克芦丁脑蛋白水解物治疗急性脑梗死的临床效果分析[J]. 医学理论与实践,2019,32(21):3444-3446.
[3] 张良兵,操礼琼,余尧红,等. 血栓通络汤联合曲克芦丁脑蛋白水解物对急性脑梗死炎性反应介质和神经功能的影响[J]. 中华中医药学刊,2020,38(7):204-207.
[4] 张晖,张华,刘平,等. 曲克芦丁脑蛋白水解物注射液治疗脑梗死的系统评价与Meta分析[J]. 中国新药杂志,2019,28(17):2170-2176.
[5] 沈杰,王燕.菖蒲醒神汤联合脑蛋白水解物治疗急性脑梗死并意识障碍患者的临床疗效[J]. 实用心脑肺血管病杂志,2019,27(5):76-80.
[6] 郝绍江.丹红联合小牛血清去蛋白治疗急性脑梗死的疗效及对患者日常生活能力的影响[J]. 山西医药杂志,2019,48(11):1311-1313.
[7] 王欣蕾,张雪,岳赞,等. 注射用脑蛋白水解物(Ⅱ)对急性脑梗死患者的临床疗效观察[J]. 脑与神经疾病杂志,2018,26(9):534-538.
[8] 曹宇晶,黄欢欢,段丹辉,等. 丹红注射液治疗急性脑梗死的临床疗效和安全性分析[J]. 河北医学,2019,25(4):676-679.
[9] 李清华,侯双兴,杨化兰,等. 丹红注射液联合丁苯酞注射液对急性脑梗死病人BDNF、NPY和NSE的影响[J]. 中西医结合心脑血管病杂志,2020,18(7):1148-1151.
[10] 朱华军,黄艳,王琼.果糖二磷酸钠片联合脑蛋白水解物对老年急性脑梗死病人血管内皮损伤和神经功能恢复的影响[J]. 中西医结合心脑血管病杂志,2018,16(12):1746-1749.
[11] 张克飞,王兵.曲克芦丁脑蛋白水解物联合多奈哌齐对老年帕金森病病人免疫功能及神经功能的影响[J]. 实用老年医学,2019,33(12):1221-1225.
[12] 马世俊.通窍活血汤联合曲克芦丁脑蛋白水解物注射液对微创颅内血肿清除术后患者神经功能及血清IMA的影响[J]. 现代中西医结合杂志,2019,28(13):1404-1407.
[13] 宋祥,杨明刚. 丹红注射液联合常规治疗在急性脑梗死患者中的应用价值[J]. 现代中西医结合杂志,2014,23(14): 1522-1524.
[14] FLETCHER A P,ALKJAERSIG N,LEWIS M,et al.A pilot study of urokinasetherapy in cerebral infarction [J]. Stroke,2016,7 (2): 135-138.
[15] 黄勇.丹红注射液对急性脑梗死患者临床疗效及对氧化应激、NIHSS评分的影响[J]. 血栓与止血学,2018,24(3):414-415.

丹红联合曲克芦丁脑蛋白水解物治疗急性脑梗死疗效分析

Therapeutic effect of Danhong combined with troxerutin cerebroprotein hydrolysate in the treatment of acute cerebral infarction

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 0

编辑推荐

Metrics

本文评价