首发TIA/缺血性轻型卒中患者认知功能损害的状况分析

doi:10.3969/j.issn.1000-8535.2020.05.011

广州医药 ›› 2020, Vol. 51 ›› Issue (5): 50-54.DOI: 10.3969/j.issn.1000-8535.2020.05.011

首发TIA/缺血性轻型卒中患者认知功能损害的状况分析

梁健欣, 黄华锰, 胡键浠, 李武英

广州市第一人民医院,华南理工大学附属第二医院(广州 510180)

收稿日期:2020-04-20 出版日期:2020-09-20 发布日期:2021-11-28

Analysis of the cognitive impairment among the patients with transient ischemic attack and minor ischemic stroke for the first attack

LIANG Jianxin, HUANG Huameng, HU Jianxi, LI Wuying

Guangzhou First People's Hospital,The Second Affiliated Hospital of South China University of Technology,Guangzhou 510180,China

Received:2020-04-20 Online:2020-09-20 Published:2021-11-28

摘要/Abstract

摘要： 目的对首发短暂性脑缺血发作(TIA)及缺血性轻型卒中的患者进行认知功能分析,评估其认知损害程度及常见的认知损害领域,以便制定早期的认知功能康复计划,减少痴呆的发生。方法纳入起病10天内的首发TIA及缺血性轻型卒中患者,完善MMSE和MoCA评分,把MMSE评分正常者划分为MoCA正常组和MoCA异常者,比较两组的认知功能损害程度及损害领域。结果纳入142例患者,MMSE正常者113例,其中MoCA正常组83例,MoCA异常组30例。两组的认知功能比较,在视空间/执行功能、命名、注意力、计算、延迟记忆、定向力等方面的差异有统计学意义(P＜0.05),在言语流畅、抽象思维方面的差异无统计学意义(P＞0.05)。结论 TIA/轻型卒中患者存在多方面不同程度的认知功能损害,临床上需重视对该类患者的认知筛查,及时了解患者认知功能的变化,以便给予及时的诊断和治疗。

关键词: 首发, 短暂性脑缺血发作, 缺血性轻型卒中, 认知功能

Abstract: Objective To analyze the cognitive impairment among the paitents with TIA and minor ischemic stroke for the first attack. Making a recovery plan in early time by eveluating the degree and domains of the cognitive impairment, so as to reduce the prevelance of dimentia. Methods Patients with TIA and minor ischemic stroke for the first attack in 10 days were included. MMSE and MoCA were completed, we sorted out the normal MMSE patients and divided them into MoCA normal group and MoCA abnormal group, compared the cognitive function between the two groups. Results 142 patients were included. Among them 113 patients' MMSE were normal, in which MoCA normal group were with 83 patients and MoCA abnormal group with 30 patients. There were significant differences between them in visuospatial and executive function, naming, attention, caculation, delay memory and orientation(P＜0.05), while no significant difference in language fluency and abstraction(P＞0.05). Conclusion Cognitive impairment of TIA/minor ischemic stroke patients was in different degree, so we should pay more attention to their cognitive function and give them an in-time diagnosis and treatment.

Key words: First attack, Transient ischemic attack, Minor ischemic stroke, Cognitive function

梁健欣, 黄华锰, 胡键浠, 李武英. 首发TIA/缺血性轻型卒中患者认知功能损害的状况分析[J]. 广州医药, 2020, 51(5): 50-54.

LIANG Jianxin, HUANG Huameng, HU Jianxi, LI Wuying. Analysis of the cognitive impairment among the patients with transient ischemic attack and minor ischemic stroke for the first attack[J]. Guangzhou Medical Journal, 2020, 51(5): 50-54.

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首发TIA/缺血性轻型卒中患者认知功能损害的状况分析

Analysis of the cognitive impairment among the patients with transient ischemic attack and minor ischemic stroke for the first attack

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