帕金森病与血管性帕金森综合征患者磁敏感加权成像的应用价值探析

doi:10.3969/j.issn.1000-8535.2018.03.032

广州医药 ›› 2018, Vol. 49 ›› Issue (3): 109-112.DOI: 10.3969/j.issn.1000-8535.2018.03.032

帕金森病与血管性帕金森综合征患者磁敏感加权成像的应用价值探析

魏易琼, 苏常春, 李泽, 赖丽莎

广州市第一人民医院(广州 510180)

收稿日期:2018-02-04 出版日期:2018-05-20 发布日期:2021-12-01
通讯作者: 李泽,E-mail:weiyiqiong1107@sina.com
基金资助:
广州市医药卫生科技项目(20151A011010)

Application value of SWI in patients with Parkinson's disease and vascular Parkinson's syndrome

WEI Yiqiong, SU Changchun, LI Ze, LAI Lisha

Received:2018-02-04 Online:2018-05-20 Published:2021-12-01

摘要/Abstract

摘要： 目的探究磁敏感加权成像(SWI)对帕金森病(PD)与血管性帕金森综合征(VPS)的鉴别诊断价值。方法回顾性分析我院2013年1月—2016年12月收治的30例PD患者(PD组)和30例VPS患者(VPS)组SWI分析结果,比较两组患者的脑椎体外系各核团的相位值差异,同时将两组患者的测量值与来我院行常规体检的正常者作为对照组进行测量比较。结果 PD组患者的黑质致密带(SNc)、苍白球(GP)、壳核(PUT)相位值较VPS组、对照组更低,组间数据对比有差异(P<0.05);而对照组的SNc、GP、PUT的相位值与VPS组相比无差异(P>0.05);三组对象的红核(RN)、尾状核(CN)测量值无差异(P>0.05);采用Hoehn&Yahr对PD患者和VPS进行分级后发现,各级PD患者SNc相位值之间差异均有统计学意义(P＜0.05),VPS组Ⅰ~Ⅱ级、III级与IV级患者相比,SNc、PUT、尾状核(CN)有统计学差异(P<0.05),而RN相位值无差异(P>0.05)。结论采用磁敏感加权成像对PD患者和VPS患者的椎体外系各核团的相位值进行测量,能对两者的鉴别起到较大的参考价值。

关键词: 帕金森病, 血管性帕金森综合征, 磁敏感加权成像

Abstract: Objective To explore the value of magnetic susceptibility weighted imaging (SWI) in the differential diagnosis of Parkinson's disease (PD) and vascularized Parkinson's syndrome (VPS). Methods The results of SWI analysis of 30 patients with PD (PD) and 30 patients with VPS (VPS) from January 2013 to December 2016 were retrospectively analyzed. The results were compared between the two groups. Of the phase value of the difference between the two groups of patients with the measured values and routine examination of our hospital as a control group for comparison. Results The phase values of the substantia nigra (SNc), globus pallidus (GP) and crustal nucleus (PUT) were significantly lower in the PD group than in the VPS group and the control group (P <0.05).There was no significant difference in the GP and PUT values between the control group and the VPS group (P> 0.05).There was no significant difference in the red nuclei (RN) between the three groups (P> 0.05).There was significant difference in SNc phase values between PD patients at all levels (P <0.05). Compared with patients with grade IV, grade I and II were higher than those of patients with grade IV (P <0.05), and the difference was statistically significant (P <0.05) between PD patients and VPS. (P <0.05), but there was no significant difference (P> 0.05) between the PUT and the caudate nucleus (CN). Conclusion The phase value of the nucleus of the vertebral body in PD patients and VPS patients was measured by magnetic susceptibility weighted imaging, which could be used as a reference for the identification of the two.

Key words: Parkinson's disease, Vascularized Parkinson's syndrome, Magnetic susceptibility weighted imaging

魏易琼, 苏常春, 李泽, 赖丽莎. 帕金森病与血管性帕金森综合征患者磁敏感加权成像的应用价值探析[J]. 广州医药, 2018, 49(3): 109-112.

WEI Yiqiong, SU Changchun, LI Ze, LAI Lisha. Application value of SWI in patients with Parkinson's disease and vascular Parkinson's syndrome[J]. Guangzhou Medical Journal, 2018, 49(3): 109-112.

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帕金森病与血管性帕金森综合征患者磁敏感加权成像的应用价值探析

Application value of SWI in patients with Parkinson's disease and vascular Parkinson's syndrome

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