RD105缺失基因检测法用于青海省北京/W系结核分枝杆菌鉴定

doi:10.3969/j.issn.1000-8535.2015.05.004

广州医药 ›› 2015, Vol. 46 ›› Issue (5): 11-14.DOI: 10.3969/j.issn.1000-8535.2015.05.004

RD105缺失基因检测法用于青海省北京/W系结核分枝杆菌鉴定

李斌¹, 文飞², 刘寿¹, 杜文琪¹, 汪海静¹, 文国颖¹, 苏效东¹, 瞿述根¹, 王兆芬¹

1 青海大学医学院(青海 810100)
2 西宁市第一人民医院(青海 810100)

收稿日期:2015-05-06 发布日期:2021-11-30
通讯作者: 王兆芬,E-mail:kristy@126.com
基金资助:
青海大学医学院中青年科研基金(2013-KY-02);青海省科技厅自然科学基金面上项目(2014-ZJ-910)

Identification of Beijing/W lineage mycobacterium tuberculosis in Qinghai province by using an RD105 deletion test

Li Bin, Wen Fei, Liu Shou, Du Wenqi, et al

Medical College of Qinghai University, Qinghai 810100,China;
Xinig City First People's Hospital, Qinghai 810100, China

Received:2015-05-06 Published:2021-11-30

摘要/Abstract

摘要： 目的了解青海省北京/W系结核分枝杆菌分布特征。方法收集青海地区结核分支杆菌临床分离株,采用RD105缺失基因检测鉴定北京/W系结核分枝杆菌。结果共收集237株结核分枝杆菌临床分离株,采用RD105缺失基因检测鉴定北京/W系结核分枝杆菌220株,占92.8%,非北京/W结核分枝杆菌,共17株,占7.2%。北京/W系结核分枝杆菌在青海地区性别与民族分布差异没有统计学意义(P＞0.05)。结论北京/W结核分枝杆菌为青海地区流行菌株,在人群易于发生感染和传播。

关键词: 结核分支杆菌, RD105, 北京/W系结核分枝杆菌

Abstract: Objective To ascertain the epidemiological characteristics of Beijing/W lineage Mycobacterium tuberculosis in Qinghai Province. Methods M. tuberculosis clinical isolates were collected and identified with an RD105 deletion test.Statistical analysis was performed by using the test. Results Totally, 237 clinical isolates of M. tuberculosis were collected in which 220 strains (92.8%) belonged to the Beijing/W lineage of M. tuberculosis while 17strains (7.2%) belonged to the non-Beijing/W lineage of M. tuberculosis according to the RD105 deletion test. There were no significant differences in the distribution of Beijing/W lineage of M. tuberculosis in the gender and nationality (P＞0.05). Conclusion Beijing/W lineage of M. tuberculosis were prevalent in Qinghai province and prone to having infection and transmission in the crowd.

Key words: Mycobacterium tuberculosis, RD105, Beijing/W lineage Mycobacterium tuberculosis

李斌, 文飞, 刘寿, 杜文琪, 汪海静, 文国颖, 苏效东, 瞿述根, 王兆芬. RD105缺失基因检测法用于青海省北京/W系结核分枝杆菌鉴定[J]. 广州医药, 2015, 46(5): 11-14.

Li Bin, Wen Fei, Liu Shou, Du Wenqi, et al. Identification of Beijing/W lineage mycobacterium tuberculosis in Qinghai province by using an RD105 deletion test[J]. Guangzhou Medical Journal, 2015, 46(5): 11-14.

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RD105缺失基因检测法用于青海省北京/W系结核分枝杆菌鉴定

Identification of Beijing/W lineage mycobacterium tuberculosis in Qinghai province by using an RD105 deletion test

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