广州医药 ›› 2021, Vol. 52 ›› Issue (5): 80-82.DOI: 10.3969/j.issn.1000-8535.2021.05.017

• 论著 • 上一篇    下一篇

五苓散治疗蛛网膜下腔出血并发脑耗盐综合征

卢鸿基1, 郑玉兰2, 王立新1   

  1. 1 广州中医药大学第二临床医学院,广东省中医院(广州 510120);
    2 祈福医院(广州 511495)
  • 收稿日期:2021-03-03 出版日期:2021-09-20 发布日期:2021-11-24
  • 通讯作者: 王立新,E-mail:plawlx@163.com
  • 基金资助:
    广东省中医药局科研项目(20202076)

Wuling powder treating subarachnoid hemorrhage complicated with cerebral salt wasting syndrome

LU Hongji1, ZHENG Yulan2, WANG Lixin1   

  1. 1 Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120,China;
    2 Clifford Hospital, Guangzhou 511495,China
  • Received:2021-03-03 Online:2021-09-20 Published:2021-11-24

摘要: 目的 通过探讨发病机制和结合1例蛛网膜下腔出血并发脑耗盐综合征病例分析,提高临床上对此类少见疾病的认识。方法 回顾性分析蛛网膜下腔出血并发脑耗盐综合征病例,运用“阴阳”、“六经”理论阐述疾病的中医病机及五苓散的中西医作用机制。结果 通过回顾性对比,使用五苓散组的患者明显比其他患者的病程短(五苓散组7.83±2.25天,对照组11.84±2.51天,P<0.05),差异有统计学意义,说明五苓散能够缩短脑耗盐综合征的病程。结论 五苓散治疗蛛网膜下腔出血合并脑耗盐综合征有良好的前景,未来可以通过前瞻性病例对照研究进一步明确其疗效。

关键词: 五苓散, 蛛网膜下腔出血, 脑耗盐综合征, 六经辩证, 阴阳

Abstract: Objective By investigating the pathogenesis and analyzing a case of subarachnoid hemorrhage complicated with cerebral salt wasting syndrome, to improve the clinical understanding of this rare disease. Methods A retrospective analysis of cases of subarachnoid hemorrhage complicated with cerebral salt wasting syndrome was made, using the theory of “yin and yang” and “six classics” to explain the pathogenesis of the disease and the mechanism of Chinese and Western medicine of Wuling powder. Results Through retrospective comparison, patients in the Wuling powder group had a shorter course of disease than other patients [(7.83±2.25) days in the Wuling powder group, (11.84±2.51) days in the control group, P<0.05], and there was a significant statistical difference, indicating that Wuling powder can shorten the course of cerebral salt wasting syndrome. Conclusion Wuling powder has a good prospect in the treatment of subarachnoid hemorrhage complicated with cerebral salt wasting syndrome, and its efficacy can be further clarified through prospective case-control studies in the future.

Key words: Wuling powder, subarachnoid hemorrhage, cerebral salt wasting syndrome, six classics dialectics, yin and yang