广州医药 ›› 2020, Vol. 51 ›› Issue (3): 65-69.DOI: 10.3969/j.issn.1000-8535.2020.03.015

• 论著 • 上一篇    下一篇

产前超声联合磁共振诊断胎儿部分性胼胝体发育不全

尚宁1, 张玉兰1, 舒爽1, 杨朝湘2, 韩鹏慧2, 黄汉林3   

  1. 1 广东省妇幼保健院超声诊断科(广州 511400)
    2 广东省妇幼保健院放射科(广州 511400)
    3 广东省妇幼保健院院长室(广州 511400)
  • 收稿日期:2020-02-05 出版日期:2020-05-20 发布日期:2021-11-28
  • 通讯作者: 黄汉林,E-mail:551885833@qq.com
  • 基金资助:
    广东省省级科技计划项目(2016A020249001)

The diagnosis of partial agenesis of the corpus callosum in fetuses by prenatal ultrasound combined with magnetic resonance imaging

SHANG Ning1, ZHANG Yulan1, SHU Shuang1, YANG Chaoxiang2, HAN Penghui2, HUANG Hanlin3   

  1. 1 Department of Ultrasound, Guangdong Women and Children Hospital, Guangzhou 511400,China
    2 Department of Radiology, Guangdong Women and Children Hospital, Guangzhou 511400, China
    3 The President's Office, Guangdong Women and Children Hospital,Guangzhou 511400,China
  • Received:2020-02-05 Online:2020-05-20 Published:2021-11-28

摘要: 目的 探讨产前超声联合磁共振诊断胎儿部分性胼胝体发育不全的价值。方法 收集产前超声联合磁共振诊断为部分性胼胝体发育不全的胎儿15例,对比出生或引产后的检查结果,分析产前超声特征。结果 产前超声直接征象:胼胝体正中矢状切面相应部位缺失12例(12/15,80.0%)。间接征象:透明隔腔形态异常(80.0%)、侧脑室扩张(73.3%)、大脑纵裂池分离(73.3%)、脑中线丘脑后方囊性包块(26.7%)、侧脑室“泪滴状改变”(26.7%)、胼周动脉走行异常(26.7%),合并颅内或其他系统畸形6例。对比出生或引产后随访结果,诊断准确率:产前超声80.0%,产前磁共振93.3%。结论 超声可以诊断胎儿部分性胼胝体发育不全,更精确的诊断建议结合产前胎儿头颅磁共振检查。

关键词: 超声检查, 产前, 部分性胼胝体发育不全, 磁共振成像

Abstract: Objective To explore the value of prenatal ultrasound in diagnosis of fetal partial agenesis of corpus callosum. Methods 15 fetuses diagnosed as partial agenesis of corpus callosum by prenatal ultrasound combined with magnetic resonance imaging (MRI) were collected. Results of examination after birth or induction of labor were compared to analyze the characteristics of prenatal ultrasound. Results Direct signs were observed in the prenatal sonographic features: 12 cases (12/15, 80.0%) were missing corresponding parts in the midsagittal section of corpus callosum. Indirect signs: transparent partition morphological abnormalities (80.0%), lateral ventricle expansion (73.3%), separation of longitudinal crack on the brain pool(73.3%), posterior thalamic midline cystic mass (26.7%), “teardrop change” of the lateral ventricle (26.7%), abnormal course of pericallosal artery (26.7%), with intracranial and other system deformity in 6 cases, including multiple anomalies. Compared with the follow-up results after birth or induction of labor, the diagnostic accuracy was 80.0% of prenatal ultrasound and 93.3% of prenatal MRI. Conclusion Ultrasonography may diagnose fetal partial agenesis of corpus callosum properly, and more accurate diagnosis could be finished combining with prenatal fetal cranial MRI.

Key words: Ultrasonic examination, Prenatal, Partial agenesis of corpus callosum, Magnetic resonance imaging