红细胞分布宽度对稳定性冠心病的预测价值

doi:10.3969/j.issn.1000-8535.2019.03.004

广州医药 ›› 2019, Vol. 50 ›› Issue (3): 14-17.DOI: 10.3969/j.issn.1000-8535.2019.03.004

红细胞分布宽度对稳定性冠心病的预测价值

张岳飞¹, 郭辉芳¹, 李永陟¹, 文平¹, 王忠²

1 新疆石河子大学医学院 (石河子 832002)
2 新疆石河子大学医学院第一附属医院心内二科(石河子 832002)

收稿日期:2019-01-22 出版日期:2019-05-20 发布日期:2021-12-17
通讯作者: 王忠,E-mail: wangzshz@163.com

Predictive value of red cell distribution width for stable coronary artery disease

ZHANG Yuefei ¹, GUO Huifang¹, LI Yongzhi ¹, WEN Ping ¹, WANG Zhong²

1 Medicial College of Shihezi University, Shihezi 832002, China
2 The First Affiliated Hospital of Medical College of Shihezi University, Shihezi 832002, China

Received:2019-01-22 Online:2019-05-20 Published:2021-12-17

摘要/Abstract

摘要： 目的探讨红细胞分布宽度(RDW)与稳定性冠心病的冠脉病变严重程度的关系,评价RDW对稳定性冠心病的预测价值。方法收集我院2016年11月—2018年11月期间因胸痛住院的患者330例,根据冠脉造影确诊稳定性冠心病组200例,除外冠心病130例为对照组。比较2组RDW水平的差异,分析RDW与冠脉病变严重程度(Gensini评分)的相关性及稳定性冠心病的独立危险因素。结果稳定性冠心病组RDW水平高于对照组(P<0.05),稳定性冠心病组RDW与 Gensini评分之间存在正相关(r=0.217,P=0.002);多因素logistic回归分析显示RDW(OR=2.950,95%CI: 1.986~4.381,P<0.001)是稳定性冠心病的独立危险因子。结论 RDW与稳定性冠心病的冠脉病变严重程度呈正相关,RDW是稳定性冠心病的独立危险因素,为稳定性冠心病的诊断提供一定预测价值。

关键词: 稳定性冠心病, 红细胞分布宽度, Gensini评分, logistic回归

Abstract: Objective To investigate the relationship between the distribution width of red blood cells (RDW) and the severity of coronary artery disease in stable coronary artery disease(SCAD), and to evaluate the predictive value of RDW for SCAD. Methods Patients who were hospitalized for chest pain from November 2016 to November 2018 were enrolled (n=330). According to coronary angiography,200 patients were divided into SCAD group (n=200),except for the SCAD group, the remaining 130 cases were the control group(n=130). The differences of RDW levels between the two groups were compared, and the correlation between RDW and severity of coronary artery disease (Gensini score) and independent risk factors for SCAD were analyzed. Results The RDW level in the SCAD group was higher than that in the control group (P<0.05). There was a positive correlation between the RDW and Gensini scores in the SCAD group (r=0.217,P=0.002). Multivariate logistic regression analysis showed RDW (OR=2.950, 95% CI: 1.986~4.381, P<0.001) is an independent risk factor for SCAD. Conclusion RDW is positively correlated with the severity of coronary artery disease in SCAD. RDW is independent risk factor of SCAD and provides predictive value for the diagnosis of SCAD.

Key words: Stable coronary artery disease, Red blood cell distribution width, Gensini score, Logistic regression

张岳飞, 郭辉芳, 李永陟, 文平, 王忠. 红细胞分布宽度对稳定性冠心病的预测价值[J]. 广州医药, 2019, 50(3): 14-17.

ZHANG Yuefei , GUO Huifang, LI Yongzhi , WEN Ping , WANG Zhong. Predictive value of red cell distribution width for stable coronary artery disease[J]. Guangzhou Medical Journal, 2019, 50(3): 14-17.

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红细胞分布宽度对稳定性冠心病的预测价值

Predictive value of red cell distribution width for stable coronary artery disease

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