注射用黄芪多糖对宫颈癌化疗患者骨髓抑制的效果分析

doi:10.3969/j.issn.1000-8535.2016.05.013

广州医药 ›› 2016, Vol. 47 ›› Issue (5): 36-38.DOI: 10.3969/j.issn.1000-8535.2016.05.013

注射用黄芪多糖对宫颈癌化疗患者骨髓抑制的效果分析

李明尧, 朱土福, 张春宁

广东省茂名市人民医院肿瘤一科(茂名 525000)

收稿日期:2016-06-10 出版日期:2016-09-20 发布日期:2021-12-02

Clinical effect of astragalus polysaccharides on protecting marrow suppression of cervical carcinoma after chemotherapy

Li Mingyao, Zhu Tufu, Zhang Chunning

People's Hospital Of Maoming, Maoming 525000, China

Received:2016-06-10 Online:2016-09-20 Published:2021-12-02

摘要/Abstract

摘要： 目的探讨注射用黄芪多糖对宫颈癌化疗患者骨髓抑制的影响。方法选取2012年11月—2015年10月于我院接受治疗的宫颈癌患者110例,随机分为对照组和观察组,每组各55例,两组患者均接受紫杉醇联合顺铂同步放疗,而观察组患者在此基础上接受每日静脉滴注注射用黄芪多糖治疗,连续应用10天。对比分析两组患者的临床疗效以及治疗前后的血象。结果经过治疗后,观察组的治疗总有效率为61.81%,明显高于对照组的38.18%,差异有统计学意义(P<0.05);两组患者经过放化疗后其白细胞、红细胞和血小板计数均有不同程度的降低,而与对照组相比,观察组患者下降不明显。结论注射用黄芪多糖可以减轻宫颈癌放化疗所致的骨髓抑制,对骨髓具有一定的保护作用,在临床治疗宫颈癌的过程中值得推广应用。

关键词: 注射用黄芪多糖, 宫颈癌, 放化疗, 骨髓抑制

Abstract: Objective To explore the clinical effect of astragalus polysaccharides on protecting marrow suppression of cervical carcinoma after chemotherapy. Methods 110 cases of patients with cervical carcinoma treated in our hospital from November 2012 to October 2015 in our hospital were selected and divided into control group and observation group, each group contains 55 cases. Both groups of patients received radiotherapy and chemotherapy of paclitaxel combined with cisplatin, and the observation group additionally received intravenous injection of astragalus polysaccharides for 10 days, to compare the hemogram before and after treatments between two groups. Results After treatments, the total effective rate of the observation group was 61.81%, significantly higher than that of the control group, the difference was statistically significant (P<0.05); The white blood cell, red blood cell and platelet count reduced in two goups after treatment. Compared with the control group, there was no significant decrease in the observation group. Conclusion Astragalus polysaccharides injection may reduce the marrow suppression induced by radiotherapy and chemotherapy in the treatment of cervical cancer, and it has a protective effect on the bone marrow.

Key words: Astragalus Polysaccharides Injection, Cervical Carcinoma, Radiotherapy and Chemotherapy, Marrow Suppression

李明尧, 朱土福, 张春宁. 注射用黄芪多糖对宫颈癌化疗患者骨髓抑制的效果分析[J]. 广州医药, 2016, 47(5): 36-38.

Li Mingyao, Zhu Tufu, Zhang Chunning. Clinical effect of astragalus polysaccharides on protecting marrow suppression of cervical carcinoma after chemotherapy[J]. Guangzhou Medical Journal, 2016, 47(5): 36-38.

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注射用黄芪多糖对宫颈癌化疗患者骨髓抑制的效果分析

Clinical effect of astragalus polysaccharides on protecting marrow suppression of cervical carcinoma after chemotherapy

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