cTBNA与EBUS-TBNA在肺门及纵膈淋巴结肿大疾病诊断中的比较

doi:10.3969/j.issn.1000-8535.2016.03.008

广州医药 ›› 2016, Vol. 47 ›› Issue (3): 22-25.DOI: 10.3969/j.issn.1000-8535.2016.03.008

cTBNA与EBUS-TBNA在肺门及纵膈淋巴结肿大疾病诊断中的比较

李晓岩, 赵子文, 钟维农, 覃丽

广州市第一人民医院呼吸内科(广州 510180)

收稿日期:2016-01-05 出版日期:2016-05-20 发布日期:2021-11-30
通讯作者: 赵子文,E-mail:zhaozw@yeah.net

Endobronchial ultrasound-guided transbronchial needle aspiration EBUS-TBNA vs conventional transbronchial needle aspiration cTBNA in the diagnosis of mediastinal and hilar lymph nodes

Li Xiaoyan, Zhao Ziwen, Zhong Weinong, et al

Department of Respiratory Medicine,Guangzhou First People's Hospital, Guagzhou 510180, China

Received:2016-01-05 Online:2016-05-20 Published:2021-11-30

摘要/Abstract

摘要： 目的探讨传统支气管针吸活检 (cTBNA )与超声支气管镜引导下针吸活检(EBUS-TBNA)对于肺部疾病伴有肺门及纵膈淋巴结肿大患者的诊断价值。方法 2012 年8月—2014年6月对在我院行CT检查提示肺部伴有肺门和/或纵膈淋巴结病变的患者38例, 分别利用cTBNA或EBUS-TBNA检查对肿大的淋巴结行TBNA,对所获得的标本进行相应的细胞学检查。结果 38例病例均经组织病理学诊断后确诊,并经过6个月的随访,其中cTBNA组(n=19)经组织病理明确诊断的包括:1例结核,5例小细胞肺癌,6例腺癌,3例鳞癌,1例大细胞癌,3例慢性炎症,cTBNA细胞学诊断阳性诊断率为63.16%(12/19),cTBNA组细胞学诊断肺癌的敏感度为66.67％(10/15),特异度为100％。EBUS-TBNA组(n=19)组织病理学诊断明确的1例为肺结核,1例为纵隔恶性肿瘤,1例为结节病,1例大细胞癌,1例小细胞癌,7例腺癌,5例鳞癌,2例为慢性炎症,EBUS-TBNA细胞学阳性诊断率为78.94%(15/19)。两种方法在诊断肺门及纵膈淋巴结肿大的疾病中有差异(P<0.05)。EBUS-TBNA组细胞学诊断肺癌的敏感度为86.67％(13/15),特异度为100％。结论 EBUS-TBNA细胞学检查对肺部疾病伴有肺门及纵膈淋巴结肿大的诊断率较cTBNA高,可明显提高检查阳性率,具有重要临床意义。

关键词: cTBNA, EBUS-TBNA, 肺门及纵膈淋巴结肿大

Abstract: Objective To evaluate the value of clinical application between cTBNA and EBUS-TBNA in diagnosis of mediastinal and hilar lymph nodes. Methods Between August 2012 and June 2014, 38 in-patients with mediastinal and hilar lymph nodes took conventional transbronchial needle aspiration( cTBNA,n=19) or endobronchial ultrasound-guided transbronchial needle aspiration(EBUS-TBNA, n=19), and we were comparing the diagnostic results of two methods. Results 19 patients in the cTBNA group were diagnosed by forceps biopsy,including 1 case of lung cancer and 162 cases of tuberculosis, 5 cases of small cell lung cancer, 6 cases of adenocarcinoma, 3 cases of squamous cell carcinoma, 1 case of large cell carcinoma, 3 cases of chronic inflammation, a cytological diagnosis of TBNA positive in 12 cases (63.16%). In the EBUS-TBNA group (n=19), the patients were diagnosed by accepting forceps biopsy, 1 case of tuberculosis, 1 case of mediastinal malignant tumor, 1 cases of sarcoidosis, 1 cases of large cell carcinoma, 1 case of small cell carcinoma, 7 cases of adenocarcinoma, 5 cases of squamous cell carcinoma, 2 cases of chronic inflammation, EBUS-TBNA cytology positive rate of diagnosis was 14 (73.68%). Two techniques in the diagnosis of mediastinal and hilar lymph nodes have statistically significant(P<0.05). The sensitinty of cytology in the diagnosis of lung caner was 86.67%(13/15),and the specificity was 100%(EBUS-TBNA). Conclusion EBUS-TBNA is an effective tool in the diagnosis of mediastinal and hilar lymph nodes and superior to cTBNA.

Key words: Conventional transbronchial needle aspiration(cTBNA), Endobronchial ultrasound-guided transbronchial needle aspiration(EBUS-TBNA), Mediastinal and hilar lymph nodes

李晓岩, 赵子文, 钟维农, 覃丽. cTBNA与EBUS-TBNA在肺门及纵膈淋巴结肿大疾病诊断中的比较[J]. 广州医药, 2016, 47(3): 22-25.

Li Xiaoyan, Zhao Ziwen, Zhong Weinong, et al. Endobronchial ultrasound-guided transbronchial needle aspiration EBUS-TBNA vs conventional transbronchial needle aspiration cTBNA in the diagnosis of mediastinal and hilar lymph nodes[J]. Guangzhou Medical Journal, 2016, 47(3): 22-25.

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cTBNA与EBUS-TBNA在肺门及纵膈淋巴结肿大疾病诊断中的比较

Endobronchial ultrasound-guided transbronchial needle aspiration EBUS-TBNA vs conventional transbronchial needle aspiration cTBNA in the diagnosis of mediastinal and hilar lymph nodes

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