表2 训练集单因素和多因素分析
变量 | β | S.E | Z | P | HR (95%CI) | m_β | m_S.E | m_Z | aP | aHR (95%CI) |
|---|---|---|---|---|---|---|---|---|---|---|
年龄 | −0.01 | 0.00 | −2.48 | 0.013 | 0.99 (0.99 ~0.99) |
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婚姻状态 |
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已婚 |
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| Ref |
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丧偶 | 0.24 | 0.12 | 1.96 | 0.051 | 1.27 (1.00 ~1.62) |
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离婚 | 0.16 | 0.12 | 1.32 | 0.187 | 1.17 (0.93 ~ 1.48) |
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单身 | 0.24 | 0.10 | 2.42 | 0.016 | 1.27 (1.05 ~ 1.53) |
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未婚/同居伴侣 | −0.32 | 1.00 | −0.32 | 0.750 | 0.73 (0.10 ~ 5.17) |
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分居 | −0.17 | 0.36 | −0.47 | 0.639 | 0.85 (0.42 ~ 1.70) |
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侧别 |
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右侧 |
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| Ref |
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左侧 | −0.03 | 0.07 | −0.43 | 0.666 | 0.97 (0.84 ~1.12) |
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种族 |
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白人 |
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| Ref |
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黑人 | 0.30 | 0.09 | 3.35 | <0.001 | 1.34 (1.13 ~1.60) |
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亚裔/太平洋岛民 | −0.15 | 0.16 | −0.98 | 0.325 | 0.86 (0.63 ~1.17) |
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美洲印第安人/阿拉斯加原住民 | −0.03 | 0.58 | −0.06 | 0.955 | 0.97 (0.31 ~3.01) |
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AJCCT |
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T1 |
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| Ref |
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| Ref |
T2 | 0.81 | 0.09 | 8.74 | <0.001 | 2.24 (1.87 ~2.68) | 0.58 | 0.10 | 6.01 | <0.001 | 1.79 (1.48 - 2.17) |
T3 | 1.59 | 0.12 | 13.08 | <0.001 | 4.91 (3.87 ~6.23) | 1.16 | 0.13 | 8.71 | <0.001 | 3.18 (2.45 - 4.12) |
T4 | 2.22 | 0.13 | 16.59 | <0.001 | 9.21 (7.09 ~11.97) | 1.62 | 0.15 | 10.80 | <0.001 | 5.06 (3.77 - 6.80) |
T0/Tis | −10.96 | 786.71 | −0.01 | 0.989 | 0.00 (0.00 ~ Inf) | −12.83 | 1361.93 | −0.01 | 0.992 | 0.00 (0.00~Inf) |
AJCCN |
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N0 |
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| Ref |
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| Ref |
N3 | 2.06 | 0.13 | 16.22 | <0.001 | 7.84 (6.11 ~10.06) | 1.60 | 0.14 | 11.56 | <0.001 | 4.97 (3.79 ~ 6.53) |
N1 | 1.00 | 0.09 | 11.65 | <0.001 | 2.73 (2.30 ~3.23) | 0.81 | 0.09 | 8.80 | <0.001 | 2.26 (1.88 ~ 2.71) |
N2 | 1.50 | 0.12 | 12.69 | <0.001 | 4.49 (3.56 ~ 5.66) | 1.26 | 0.13 | 10.06 | <0.001 | 3.54 (2.76 ~ 4.52) |
AJCCM |
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M0 |
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| Ref |
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| Ref |
M1 | 5.16 | 1.02 | 5.06 | <0.001 | 174.94 (23.65~1 293.85) | 3.46 | 1.04 | 3.32 | <0.001 | 31.86 (4.13 ~245.55) |
是否发生骨转移 |
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否 |
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| Ref |
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是 | 5.16 | 1.02 | 5.06 | <0.001 | 174.94 (23.65~1 293.85) |
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Grade |
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Ⅱ |
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| Ref |
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Ⅲ | 0.33 | 0.11 | 3.15 | 0.002 | 1.39 (1.13 ~1.71) |
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Ⅳ | 0.55 | 0.39 | 1.41 | 0.157 | 1.74 (0.81 ~3.73) |
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Ⅰ | −0.50 | 0.42 | −1.18 | 0.236 | 0.61 (0.27 ~1.38) |
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是否接受过放疗 |
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否 |
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| Ref |
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| Ref |
是 | −0.04 | 0.07 | −0.53 | 0.594 | 0.96 (0.83 ~1.11) | −0.21 | 0.08 | −2.56 | 0.011 | 0.81 (0.69~ 0.95) |
是否接受过化疗 |
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否 |
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| Ref |
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| Ref |
是 | 0.22 | 0.10 | 2.34 | 0.019 | 1.25 (1.04 ~1.51) | 0.29 | 0.20 | 1.45 | 0.148 | 1.33 (0.90~1.97) |
治疗顺序 |
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无系统治疗和(或)手术 |
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| Ref |
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| Ref |
术后系统治疗 | −0.12 | 0.10 | −1.29 | 0.196 | 0.88 (0.73 ~1.07) | −0.52 | 0.19 | −2.75 | 0.006 | 0.59 (0.41 ~0.86) |
术前系统治疗 | 0.31 | 0.12 | 2.72 | 0.006 | 1.37 (1.09 ~1.71) | −0.64 | 0.20 | −3.15 | 0.002 | 0.53 (0.36 ~ 0.79) |
术前术后均进行系统治疗 | 0.63 | 0.15 | 4.12 | <0.001 | 1.87 (1.39 ~2.52) | −0.37 | 0.23 | −1.63 | 0.103 | 0.69 (0.44 ~ 1.08) |
系统治疗前后进行手术 | 0.06 | 0.29 | 0.20 | 0.842 | 1.06 (0.60~1.86) | −1.03 | 0.34 | −3.07 | 0.002 | 0.36 (0.18~ 0.69) |
术中系统治疗及术前/术后其他系统治疗 | 0.97 | 1.00 | 0.97 | 0.333 | 2.64 (0.37 ~18.87) | 1.49 | 1.02 | 1.46 | 0.145 | 4.43 (0.60~32.89) |
术中系统治疗 | −12.01 | 850.00 | −0.01 | 0.989 | 0.00 (0.00 ~Inf) | −13.59 | 1201.01 | −0.01 | 0.991 | 0.00 (0.00 ~ Inf) |