miRNAs在肝细胞肝癌发展过程中的研究进展

doi:10.3969/j.issn.1000-8535.2018.02.033

广州医药 ›› 2018, Vol. 49 ›› Issue (2): 123-126.DOI: 10.3969/j.issn.1000-8535.2018.02.033

• 综述 • 上一篇

miRNAs在肝细胞肝癌发展过程中的研究进展

矫元君, 尹耀新

北京大学深圳医院肝胆胰外科(深圳 518000)

收稿日期:2017-11-28 出版日期:2018-03-20 发布日期:2021-12-01
通讯作者: 矫元君,E-mail:360352759@qq.com

Research progess of miRNAs in hepatocellular carcinoma

JIAO Yuanjun, YIN Yaoxin

Received:2017-11-28 Online:2018-03-20 Published:2021-12-01

摘要/Abstract

摘要： 肝细胞肝癌(HCC)是世界上最常见的肿瘤之一,其病因及确切的分子机制尚不完全清楚,目前认为其发病是多因素、多步骤的复杂过程,且预后较差。miRNAs在调控细胞的周期变化中起到重要的作用,它具有较高的组织特异性,在肿瘤发生中起到关键作用,从而有潜力作为肝癌的诊断和分类的新生物标志物,以及预测患者预后的工具。本文就近年来miRNAs在肝细胞肝癌方面的研究进展做一综述。

关键词: miRNAs, 肝细胞肝癌, 发病机制, 治疗方法

矫元君, 尹耀新. miRNAs在肝细胞肝癌发展过程中的研究进展[J]. 广州医药, 2018, 49(2): 123-126.

JIAO Yuanjun, YIN Yaoxin. Research progess of miRNAs in hepatocellular carcinoma[J]. Guangzhou Medical Journal, 2018, 49(2): 123-126.

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miRNAs在肝细胞肝癌发展过程中的研究进展

Research progess of miRNAs in hepatocellular carcinoma

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