莫西沙星治疗糖尿病合并肺结核的临床疗效分析

doi:10.3969/j.issn.1000-8535.2015.05.007

广州医药 ›› 2015, Vol. 46 ›› Issue (5): 22-24.DOI: 10.3969/j.issn.1000-8535.2015.05.007

莫西沙星治疗糖尿病合并肺结核的临床疗效分析

赖晓宇, 刘桂芬, 黄惠安

惠州市惠城区慢性病防治站 (惠州 516001)

收稿日期:2015-03-13 发布日期:2021-11-30

Analysis of clinical efficacy of moxifloxacin in the treatment of diabetes complicated with pulmonary tuberculosis

Lai Xiaoyu, Liu Guifen, Huang Huian

Chronic Disease Prevention and Control Station of Huicheng District, Huizhou 516001, China

Received:2015-03-13 Published:2021-11-30

摘要/Abstract

摘要： 目的探讨莫西沙星结合抗结核药物治疗糖尿病合并肺结核患者的临床疗效分析。方法将本组126例糖尿病合并肺结核患者分为对照组(n=63)和观察组(n=63);对照组给予降血糖治疗及抗结核药物降糖治疗,观察组在对照组治疗基础上服用莫西沙星;两组治疗均以3个月为一个疗程,2个疗程后统计疗效。结果观察组总有效率(93.65%)高于对照组(76.19%),差异有统计学意义(P<0.05);观察组痰菌检测转阴率(94.59%)高于对照组(79.49%),差异有统计学意义(P<0.05);治疗过程中观察组与对照组出现不良反应情况相比较差异无统计学意义(P＞0.05)。结论莫西沙星结合抗结核药物治疗糖尿病合并肺结核疗效显著,具有较强的杀菌作用。

关键词: 莫西沙星, 抗结核药物, 糖尿病合并肺结核

Abstract: Objective To investigate the clinical efficacy of moxifloxacin combining with antituberculosis drug in the treatment of diabetic patients with pulmonary tuberculosis. Methods A group of 126 patients of diabetes complicated with pulmonary tuberculosis were divided into control group (n=63) and observation group (n=63); the control group was given by hypoglycemic therapy and therapy of antituberculosis drug only, and the observation group was also given by moxifloxacin; two groups were treated for 3 months as a course.The clinical efficacy was evaluated after 2 courses. Results The total effective rate of observation group (93.65%) was significantly higher than that of the control group (80.95%), and the difference was statistically significant (P<0.05); the negative sputum rate of observation group (94.59%) was higher than that of the control group (79.49%), and the difference was statistically significant (P<0.05); there was no statistically significant difference between the observation group and the control group in adverse effects. Conclusion The curative effect of moxifloxacin combining with antituberculosis drug in the treatment of diabetes mellitus complicated with pulmonary tuberculosis was good, with strong bactericidal effect.

Key words: Moxifloxacin, Antituberculosis drug, Diabetes complicated with pulmonary tuberculosis

赖晓宇, 刘桂芬, 黄惠安. 莫西沙星治疗糖尿病合并肺结核的临床疗效分析[J]. 广州医药, 2015, 46(5): 22-24.

Lai Xiaoyu, Liu Guifen, Huang Huian. Analysis of clinical efficacy of moxifloxacin in the treatment of diabetes complicated with pulmonary tuberculosis[J]. Guangzhou Medical Journal, 2015, 46(5): 22-24.

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莫西沙星治疗糖尿病合并肺结核的临床疗效分析

Analysis of clinical efficacy of moxifloxacin in the treatment of diabetes complicated with pulmonary tuberculosis

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