广州医药 ›› 2015, Vol. 46 ›› Issue (2): 81-83.DOI: 10.3969/j.issn.1000-8535.2015.02.031

• 临床诊疗 • 上一篇    下一篇

妈富隆治疗围绝经期功血的临床效果观察

蔡青红, 何旭霞   

  1. 广州市黄埔区人口和计划生育服务站(广州 510700)
  • 收稿日期:2014-11-25 发布日期:2021-11-30
  • 通讯作者: 蔡青红,E-mail:337466541@qq.com

Observation of clinical effect of Marvelon on perimenopausal dysfunctional uterine bleeding

Cai Qinghong, He Xuxia   

  1. Huangpu District, Guangzhou City, Guangdong Province, population and family planning service station
  • Received:2014-11-25 Published:2021-11-30

摘要: 目的 探讨妈富隆用于治疗围绝经期功血的临床效果。方法 选择年龄40~53岁的出现围绝经期功血的育龄妇女100例。采用盲选法随机分为观察组和对照组,每组各50例。观察组诊刮后第5天开始口服妈富隆,开始每次服1片,每8 h服1次,血止后每3天递减1/3剂量,至维持量1片/天,共计21天,停药后撤退性出血的第5天开始服下周期的药;对照组诊刮后第15天开始口服醋酸甲羟孕酮片,10 mg/天,连服10 天停药后撤退性出血的第15天开始服下周期的药;两组各连服3个周期。结果 观察组服药后阴道流血控制时间和完全止血时间明显短于对照组,在治疗效果方面,观察组总有效率90%,对照组48%,观察组疗效优于对照组。结论 妈富隆治疗围绝经期功血的效果优于孕激素后半周期治疗围绝经期功血的效果,临床上值得推广。

关键词: 妈富隆, 围绝经期功血, 醋酸甲羟孕酮片, 临床效果

Abstract: Objective To investigate the clinical effect of Marvelonon perimenopausal dysfunctional uterine bleeding. Methods Select the age 40-53 year old appearance ofperimenopausal dysfunctional uterine bleeding of 100 women of childbearing age. The blind were randomly divided into the observation group and the control groupmethod, 50 cases in each group. The observation group and curettage fifth days after the start of Marvelon, begin to take 1 tablets eachtime, every 8 h 1 times, after the cessation of blood every 3 days and decreasing 1/3 dose,to maintain the volume of 1 pieces of/d, a total of 21 days, fifth days after stopping drug withdrawal bleedingbegan to take periodic drug; control group and curettagefifteenth days after the start of oral medroxyprogesterone acetate tablets, 10 mg/d, and even served fifteenth daysafter withdrawal of 10d. withdrawal bleeding began to takeperiodic drug; two of each suit 3 cycle group. Results The observation group after taking the vaginal bleedingcontrol time and complete hemostasis time significantly shorter than the control group, in treatment effect, total effective rate of observation group 90%, contrast group48%, observation group was significantly better than the control group. Conclusion Conclusion Marvelon on perimenopausal dysfunctional uterine bleeding effect is better than the second half cycleof progesterone treatment of perimenopausal dysfunctional uterine bleeding effect, is worth popularizingin clinic.

Key words: Marvelon, Perimenopausal dysfunctional uterine bleeding, Medroxyprogesterone Acetate Tablets, Clinical effect