关键词: 急性呼吸窘迫综合征, 血清甲状腺素, 相关性

Abstract: Objective To analyze serum thyroid hormone level change of acute respiratory distress syndrome and the correlation between the severity of disease. Methods 123 cases (including mild 26.67 kPa<PaO₂/FiO₂≤40.00 kPa,PEEP or CPAP≥0.49 kPa,moderate 13.33 kPa <PaO₂/FiO₂≤26.67 kPa,PEEP≥0.49 kPa and severe PaO₂/FiO₂≤13.33 kPa,PEEP≥0.49 kPa)of patients with acute respiratory distress syndrome and 41 cases of non-ARDS were involved. from January 2016 to January 2018 in our hospital and 41 cases of healthy people by routine check-up in our hospital during the same period were selected,then the serum thyroid hormone levels were determined. Results Compared with healthy control group,TSH、FT4、TT4、FTS、TT3 level in non-ARDS group has no statistical difference(P＞0.05),while compared with the rest of the two groups,all indexes in ARDS group were lower (P＜0.05). And TSH、FT4、TT4、FT3、TT3 levels in moderate ARDS group decreased compared with those in relatively mild ARDS (P＜0.05). The level of each index in severe ARDS group decreased compared with the moderate ARDS group (P＜0.05). There was statistical difference in detection index level in three groups. Conclusion The serum thyroid hormone level of ARDS patients is positively correlated with hypoxemia. As the pathological severity changes ,the level of hypoxemia changes are more apparent. Dynamic monitoring of serum thyroid hormone is of great significance in severity judgement and prognosis evaluation.

Key words: Acute respiratory distress syndrome, Serum thyroid hormone, Correlation