广州医药 ›› 2021, Vol. 52 ›› Issue (2): 54-57.DOI: 10.3969/j.issn.1000-8535.2021.02.012

• 论著 • 上一篇    下一篇

影响广州地区Rh阴性红细胞采供情况的原因

郑晓晓, 罗伟峰, 黎世杰, 陈锦艳, 关飞舜   

  1. 广州血液中心 广州市医学重点实验室 血液安全重点实验室 (广州 510095)
  • 收稿日期:2020-11-11 出版日期:2021-03-20 发布日期:2021-11-25
  • 通讯作者: 梁华钦,E-mail:lianghuaqin11@163.com
  • 基金资助:
    广州市医学重点学科建设项目(血液安全重点实验室)

Analysis on the factors affecting the collection and supply of RhD(-) red blood cells in Guangzhou city

ZHENG Xiaoxiao, LUO Weifeng, LI Shijie, CHEN Jinyan, GUAN Feishun   

  1. Guangzhou Blood Center, The Key Medical Laboratory of Guangzhou, Guangzhou 510095,China
  • Received:2020-11-11 Online:2021-03-20 Published:2021-11-25

摘要: 目的 通过回顾分析广州地区Rh阴性血的采供情况,了解Rh阴性红细胞的供应特点,更好地实施Rh阴性血液库存管理,保障输血安全。方法 统计2011—2017年广州血液中心Rh阴性血液采集量与供应量,血型及医院供血量的分布情况。结果 2011—2017年广州血液中心Rh阴性全血采集量为11 283 U,占总采血量的0.39%(11 283/2 902 485),供应总量为11 693 U,占红细胞类成分血总供应量的0.43%(11 693/2 762 229),其中悬浮红细胞供应比例逐年增加,冰冻解冻去甘油红细胞供应比例逐年下降,并从2014年起Rh阴性悬浮红细胞供应增长率明显高于血液采集增长率;4种血型供应量总体比较,差异有统计学意义(F=22.217,P<0.05),A、B型Rh阴性悬浮红细胞供应增长最快,增长率分别为137.3%和134.1%,医院分布以三级以上及综合医院为主。结论 应根据广州地区Rh阴性红细胞采供特点,来持续改进Rh阴性血源招募和采供策略。通过建立一支Rh阴性定期献血者队伍,加强Rh阴性血液统筹管理和临床科室-输血科-采供血机构的沟通,促进Rh阴性血液的供需平衡,保障Rh阴性患者输血安全。

关键词: Rh阴性血液, 血型, 血液供应

Abstract: Objective To understand the characteristics of Rh-negative red blood cells (RBC) supply, improve the management of storage and guarantee the safety of blood transfusion. The collection and supply of Rh-negative RBC in Guangzhou city was retrospectively analyzed. Methods The amount of Rh-negative RBC collection and supply, the distribution of ABO blood type and the consumption of blood by different hospitals in Guangzhou Blood Center from 2011 to 2017 were statistically analyzed. Results During 2011-2017, 11 283 U Rh-negative RBC was collected in Guangzhou Blood Center, accounting for 0.39% of total RBC collection (11 283/2 902 485); 1 693 U Rh-negative RBC was supplied, accounting for 0.43% of the total blood supply (11 693/2 762 229). The proportion of suspended RBC supply increased year by year, in contrast with the decease of proportion of frozen defrosteddeglyceal RBC supply. In addition, the growth rate of Rh-negative suspended RBC supply was higher than that of RBC collection since 2014 (F=217, P<0.05). A-and B-Rh negative suspended RBC supply increased, with growth rates of 137.3% and 134.1%, respectively. The Rh negative RBC was predominantly supplied to Grade III and general hospitals. Conclusion By establishing a team of Rh-negative regular blood donors, the strategies for recruitment, collection and supply of Rh-negative RBC should be continuously improved according to the characteristics of Rh-negative RBC collection and supply in Guangzhou. The coordinating management of Rh-negative, as well as the communication of clinical departments, departments of transfusion and blood banks should be improved. In addition, the balance between supply and demand of Rh-negative blood should be promoted, and the safety of blood transfusion for Rh-negative patients can be improved.

Key words: RhD(-)blood, Blood types, Blood supply