罗哌卡因浸润麻醉在胸腹腔镜联合食管癌根治术后镇痛疗效的临床观察

doi:10.3969/j.issn.1000-8535.2019.03.008

广州医药 ›› 2019, Vol. 50 ›› Issue (3): 30-32.DOI: 10.3969/j.issn.1000-8535.2019.03.008

罗哌卡因浸润麻醉在胸腹腔镜联合食管癌根治术后镇痛疗效的临床观察

刘翼¹, 何丹², 高胜利²

1 深圳大学总医院胸心外科 (深圳 585055)
2 新疆医科大学附属肿瘤医院胸外科 (乌鲁木齐 830011)

收稿日期:2018-11-14 出版日期:2019-05-20 发布日期:2021-12-17
通讯作者: 高胜利,E-mail: 67508432@qq.com
基金资助:
新疆维吾尔自治区自然科学基金 (2016D01C351)

Clinical observation of ropivacaine infiltration anesthesia for analgesia after thoracoscopic and laparoscopic combined radical resection of esophageal cancer

LIU Yi¹, HE Dan², GAO Shengli²

1 Department of Cardiothoracic Surgery, General Hospital of Shenzhen University, Shenzhen 518055, China
2 Department of Thoracic Surgery, Tumor Hospital Affiliated to Xinjiang Medical University, Urumqi 830011, China

Received:2018-11-14 Online:2019-05-20 Published:2021-12-17

摘要/Abstract

摘要： 目的研究罗哌卡因阻滞用于胸腹腔镜联合食管癌根治术后镇痛的临床效果。方法胸腹腔镜联合食管癌根治术患者60例,分为: 观察组(n=30),缝合切口时用0.25%盐酸罗哌卡因10 mL于切口局部浸润;对照组(n=30) 不做局部浸润麻醉处理;记录二组术后2 h、6 h、12 h、24 h、48 h的疼痛视觉模拟评分(VAS)及血浆皮质醇浓度。结果观察组术后2 h、6 h、12 h VAS评分优于对照组,术后12 h观察组血浆皮质醇浓度低于对照组。结论罗哌卡因术终阻滞术后12 h内镇痛效果明显。

关键词: 罗哌卡因, 腔镜食管癌根治术, 术后镇痛

Abstract: Objective To evaluate the efficiency of postoperative analgesia with ropivacaine block after thoracoscopic-lapacoscopic esophagectomy (TLE). Methods Totally 60 patients with esophageal cancer underwent TLE were divided into two groups: observation group(n=30)with 0.25% ropivacaine hydrochloride solution 10 mL injection around incision before end of the operation; control group(n=30)without the treatment. The VAS and the plasma Cortisol concentration at 2 h、6 h、12 h、24 h、48 h after surgery were recorded. Results The VAS at 2 h、6 h、12 h after surgery in observation group was higher than that of the control group,but not at 24 h、48 h after surgery. The plasma Cortisol concentration in the observation group was higher than that of in the control at 12 hours postoperatively. Conclusion Ropivacaine block of incision is helpful to have analgesic effect within 12 hours after TLE.

Key words: Ropivacaine, Thoracoscopic-lapacoscopic esophagectomy, Analgesia

刘翼, 何丹, 高胜利. 罗哌卡因浸润麻醉在胸腹腔镜联合食管癌根治术后镇痛疗效的临床观察[J]. 广州医药, 2019, 50(3): 30-32.

LIU Yi, HE Dan, GAO Shengli. Clinical observation of ropivacaine infiltration anesthesia for analgesia after thoracoscopic and laparoscopic combined radical resection of esophageal cancer[J]. Guangzhou Medical Journal, 2019, 50(3): 30-32.

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罗哌卡因浸润麻醉在胸腹腔镜联合食管癌根治术后镇痛疗效的临床观察

Clinical observation of ropivacaine infiltration anesthesia for analgesia after thoracoscopic and laparoscopic combined radical resection of esophageal cancer

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