关键词: 桥本甲状腺炎, 不同术式, 甲状腺乳头状癌

Abstract: Objective To explore clinical efficacy of different surgical methods in treatment of papillary thyroid cancinoma combined Hashimoto's thyroiditis. Methods Eighty-seven patients of unilateral papillary thyroid carcinoma in patients with Hashimoto's thyroiditis who were treated in our hospital between April 2015 and May 2016 were divided into two groups according to surgical treatment methods, namely observation group and control group. Forty-four patients in the observation group received ipsilateral thyroid lobe + isthmus resection, while forty-three patients in the control group were given total thyroidectomy. Changes of parathyroid and thyroid functions, intraoperative blood loss, length of incision and operation time after different surgical procedures were compared. Results The hypoparathyroidism rate (0.00%), hypothyroidism rate (2.27%), and incision length (4.00±1.10)cm, blood loss (33.60±8.30)mL, operation time (130.73±34.67)min in the observation group were lower than those in the control group (11.63%), (97.67%), (9.70±2.33)cm, (76.70±23.90)mL, (160.94±39.70) min, the difference was statistically significant (P<0.05). Conclusion Ipsilateral thyroid lobe and isthmus resection shows obvious effect in treatment of papillary thyroid carcinoma with Hashimoto's thyroiditis, effectively reduces the incidence of parathyroid and thyroid dysfunction, improves intraoperative blood loss, length of incision and operation time.

Key words: Hashimoto's thyroiditis, Different surgical pathways, Papillary thyroid carcinoma